4-Vinylphenol (10% in Propylene glycol)
Based on 2 publication(s) in Google Scholar
4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.46%
- CAS 番号: 2628-17-3
- 分子式: C8H8O
- 分子量:120.15
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保管条件:
Solution, -20°C, 2 years
MedChemExpress(MCE)の使用を引用している文献 4-Vinylphenol (10% in Propylene glycol)
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生物活性
4-Vinylphenol (12.5-200 μg/mL) significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 μg/mL[1].
4-Vinylphenol (0.15 or 0.3 μg/mL; 3 days) reduces sphere formation and vimentin expression on CSCs in breast cancer[1].
4-Vinylphenol (50, 100 μg/mL; 72 hours) significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells[1].
4-Vinylphenol (100 μg/mL) significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2628-17-3
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性状 Liquid
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分子量 120.15
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分子式 C8H8O
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Color Colorless to light yellow
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SMILES
OC1=CC=C(C=C)C=C1
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別名
4-Hydroxystyrene
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Structure Classification
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Initial Source
recombinant Streptomyces mobaraense
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Solution, -20°C, 2 years
Publications (2)
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Journal Impact Factor
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Most Recent
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Food Chem
Lactic acid bacteria decarboxylates p-coumaric acid in the presence of blueberry anthocyanins, facilitating hydroxyphenyl-pyranoanthocyanin formation. [Abstract]2026 Jun 30:515:149218. PMID: 41990504 -
Food Res Int
2025 Dec;221(Pt 3):117420. PMID: 41214930
純度とドキュメンテーション
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データシート (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)