6-アミノピリジン-3-カルボン酸
Based on 1 Customer Validation
6-Aminonicotinic acid is an analog of Niacin (HY-B0143) and also a GABAA receptor agonist with a Ki value of 4.4 μM in rats. 6-Aminonicotinic acid binds to both native and recombinant GABAA receptors, is metabolized into non-functional pyridine nucleotide analogs to inhibit dehydrogenases, and suppresses the proliferation of T2 bacteriophages. 6-Aminonicotinic acid accumulates in specific bacterial cells in the form of pyridine nucleotide analog metabolites. 6-Aminonicotinic acid can be used in research related to neurological disorders such as anxiety, epilepsy and schizophrenia, and also serves as an intermediate in organic synthesis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.56%
- CAS 番号: 3167-49-5
- 分子式: C6H6N2O2
- 分子量:138.13
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
More
生物活性
6-Aminonicotinic acid (6-ANAm) can be taken up by Escherichia coli W3899 NAm 11 cells, metabolized into multiple pyridine nucleotide analogs, and excreted in the form of 6-aminonicotinamide[1].
6-Aminonicotinic acid (compound 3) binds to native GABAA receptors in rat brain synaptic membranes, with a Ki value of 4.4 μM[2].
6-Aminonicotinic acid acts as a weak agonist at human α1β2γ2S GABAA receptors and human ρ1 GABAA receptors expressed in tsA201 cells[2].
6-Aminonicotinic acid (6-ANA) can be prepared via the electrocatalytic electrosynthesis of reducing 2-amino-5-bromopyridine on a silver cathode in a CO2-saturated solvent, with 2-aminopyridine as the major product[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 3167-49-5
-
性状 Solid
-
分子量 138.13
-
分子式 C6H6N2O2
-
Color White to light yellow
-
SMILES
O=C(O)C1=CN=C(N)C=C1
-
別名
6-Aminonicotinic acid; 3-Pyridinecarboxylic acid, 1,6-dihydro-6-imino-; 6-Aminopyridine-3-carboxylic acid; 6-アミノニコチン酸
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 2.5 mg/mL (18.10 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (272 KB)
-
SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.2396 mL | 36.1978 mL | 72.3956 mL | 180.9889 mL |
| 5 mM | 1.4479 mL | 7.2396 mL | 14.4791 mL | 36.1978 mL | |
| 10 mM | 0.7240 mL | 3.6198 mL | 7.2396 mL | 18.0989 mL | |
| 15 mM | 0.4826 mL | 2.4132 mL | 4.8264 mL | 12.0659 mL |
6-Aminonicotinic acid 関連分類
HY-W015793 関連分類
Powered by Bioz