DGAT1-IN-1
Based on 2 publication(s) in Google Scholar
DGAT1-IN-1 is a diacylglycerol O-acyltransferase 1 (DGAT1) inhibitor with a human IC50 of <10 nM and a mouse IC50 of <50 nM. DGAT1-IN-1 is applicable to the research of obesity-related diseases, type 2 diabetes and diabetes-related diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 1449779-49-0
- 分子式: C30H28F3N3O4
- 分子量:551.56
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Metabolism/Protease Compound Library
HY-L012
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Anti-diabetic Compound Library
HY-L040
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Anti-Obesity Compound Library
HY-L087
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Lipid Metabolism Compound Library
HY-L091
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Metabolic Enzyme Compound Library
HY-L146
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Bioactive Compound Library Max
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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MedChemExpress（MCE）の使用を引用している文献 DGAT1-IN-1
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生物活性
GAT1-IN-1 (example 1) blocks the key reaction of triglyceride synthesis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1449779-49-0
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性状 Solid
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分子量 551.56
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分子式 C30H28F3N3O4
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Color White to off-white
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SMILES
OC(C[C@H]1CC[C@H](C2=CC=C(C3=CN4C=C(C(NCC5=CC=C(OC(F)(F)F)C=C5)=O)N=C4C=C3)C=C2)CC1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (2)
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Journal Impact Factor
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Most Recent
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Nat Commun
2023 May 29;14(1):3100. PMID: 37248213 -
溶剤 & 溶解度
DMSO : 20 mg/mL (36.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8130 mL | 9.0652 mL | 18.1304 mL | 45.3260 mL |
| 5 mM | 0.3626 mL | 1.8130 mL | 3.6261 mL | 9.0652 mL | |
| 10 mM | 0.1813 mL | 0.9065 mL | 1.8130 mL | 4.5326 mL | |
| 15 mM | 0.1209 mL | 0.6043 mL | 1.2087 mL | 3.0217 mL | |
| 20 mM | 0.0907 mL | 0.4533 mL | 0.9065 mL | 2.2663 mL | |
| 25 mM | 0.0725 mL | 0.3626 mL | 0.7252 mL | 1.8130 mL | |
| 30 mM | 0.0604 mL | 0.3022 mL | 0.6043 mL | 1.5109 mL |
DGAT1-IN-1 関連分類
HY-12425 関連分類
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