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COX-2-IN-48

COX-2-IN-48 (5-25), a COX-2 inhibitor with an IC50 of 51.7 nM for human COX-2, exerts anti-inflammatory and analgesic effects in various rodent models by inhibiting NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, the phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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  • 分子式: C25H17ClF3NO2
  • 分子量:455.86
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • COX-2-IN-48 Chemical Structure
    COX-2-IN-48 構造式
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COX アイソフォーム固有の製品をすべて表示

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NF-κB アイソフォーム固有の製品をすべて表示

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100 mg

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  • COX-2-IN-48 Chemical Structure
    COX-2-IN-48 Chemical Structure
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  • COX-2-IN-48