CypD-IN-3
CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-3 has CypD affinity with an IC50 value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2651994-75-9
- 分子式: C53H61N7O11
- 分子量:972.09
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Cyclophilin アイソフォーム固有の製品をすべて表示
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生物活性
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Cyclophilin D 0.01 μM (IC50) |
Cyclophilin A 1.1 μM (IC50) |
Cyclophilin B 0.21 μM (IC50) |
Cyclophilin E 0.31 μM (IC50) |
CypD-IN-3 (B52) has selectivity for inhibiting CypD, CypA, CypB and CypE with IC50 values of 0.01 μM, 1.1 μM, 0.21 μM and 0.31 μM, respectively[1].
CypD-IN-3 (10 μM) inhibits mitochondrial permeability transition pore opening in isolated mitochondria[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2651994-75-9
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分子量 972.09
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分子式 C53H61N7O11
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SMILES
NCCOCCNC([C@@H]1CCNC(/C=C/C(N2CCC[C@](C2)(C(N[C@H](C(NCC3=C(CC(N1)=O)C=CC=C3)=O)CC4=CC=C(C=C4)C5=CC=C(C=C5)CC(C(O)=O)C(O)=O)=O)CC6=CC=CC=C6)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CypD-IN-3 関連分類
HY-151487 関連分類
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