(E)-4-Hydroxytamoxifen-d5
Based on 1 Customer Validation
(E)-4-Hydroxytamoxifen-d5 ((E)-Afimoxifene-d5) is the deuterium labeled (E)-4-Hydroxytamoxifen. (E)-4-Hydroxytamoxifen ((E)-Afimoxifene), the less active isomer of (Z)-4-hydroxytamoxifen, is an estrogen receptor modulator.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.28%
- 分子式: C26H24D5NO2
- 分子量:392.54
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
-
非標識Cas 174592-47-3
-
性状 Solid
-
分子量 392.54
-
分子式 C26H24D5NO2
-
Color Off-white to pink
-
SMILES
OC1=CC=C(C=C1)/C(C2=CC=C(C=C2)OCCN(C)C)=C(C([2H])([2H])C([2H])([2H])[2H])\C3=CC=CC=C3
-
別名
(E)-Afimoxifene-d5
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (254.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (272 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5475 mL | 12.7376 mL | 25.4751 mL | 63.6878 mL |
| 5 mM | 0.5095 mL | 2.5475 mL | 5.0950 mL | 12.7376 mL | |
| 10 mM | 0.2548 mL | 1.2738 mL | 2.5475 mL | 6.3688 mL | |
| 15 mM | 0.1698 mL | 0.8492 mL | 1.6983 mL | 4.2459 mL | |
| 20 mM | 0.1274 mL | 0.6369 mL | 1.2738 mL | 3.1844 mL | |
| 25 mM | 0.1019 mL | 0.5095 mL | 1.0190 mL | 2.5475 mL | |
| 30 mM | 0.0849 mL | 0.4246 mL | 0.8492 mL | 2.1229 mL | |
| 40 mM | 0.0637 mL | 0.3184 mL | 0.6369 mL | 1.5922 mL | |
| 50 mM | 0.0510 mL | 0.2548 mL | 0.5095 mL | 1.2738 mL | |
| 60 mM | 0.0425 mL | 0.2123 mL | 0.4246 mL | 1.0615 mL | |
| 80 mM | 0.0318 mL | 0.1592 mL | 0.3184 mL | 0.7961 mL | |
| 100 mM | 0.0255 mL | 0.1274 mL | 0.2548 mL | 0.6369 mL |