LMNB2 - lamin B2 Gene

Also Known as EPM9; LMN2; LAMB2; MCPH27

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 84823

About LMNB2

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:2,428,166-2,456,959 (from NCBI)

This gene has 6 transcripts (splice variants), 189 orthologues, 68 paralogues and is associated with 6 phenotypes. Ubiquitous expression in placenta (RPKM 13.1), colon (RPKM 11.1) and 25 other tissues.

Summary

This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During Mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012]

LMNB2 Products (1)

mRNA	Protein	Name
NM_032737.4	NP_116126.3	lamin-B2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	参考文献	由来
enables identical protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	24981860	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LMNB2 Protein Structure

Filament

LTD

0
100
200
300
400
500
600 a.a.

Protein Preferred Names	Protein Names
lamin-B2	epididymis secretory sperm binding protein

LMNB2 Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	LMNB2	Q03252	MID2	Homo sapiens	Q9UJV3-2	Validated Y2H	32296183
Intra	LMNB2	Q03252	MID2	Homo sapiens	Q9UJV3-2	Y2H Array	32296183
Intra	LMNB2	Q03252	MID2	Homo sapiens	Q9UJV3-2	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	ZFHX3	Homo sapiens	Q15911-2	Validated Y2H	32296183
Intra	LMNB2	Q03252	TSGA10IP	Homo sapiens	Q3SY00	Validated Y2H	32296183
Intra	LMNB2	Q03252	FH	Homo sapiens	P07954	Y2H Array	32296183
Intra	LMNB2	Q03252	FH	Homo sapiens	P07954	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	PPP1R13B	Homo sapiens	Q96KQ4	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	PPP1R13B	Homo sapiens	Q96KQ4	Validated Y2H	32296183
Intra	LMNB2	Q03252	PPP1R13B	Homo sapiens	Q96KQ4	Y2H Array	32296183
Intra	LMNB2	Q03252	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	TFIP11	Homo sapiens	Q9UBB9	Validated Y2H	32296183
Intra	LMNB2	Q03252	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	32296183
Intra	LMNB2	Q03252	TP53BP2	Homo sapiens	Q05BL1	Y2H Array	32296183
Intra	LMNB2	Q03252	TP53BP2	Homo sapiens	Q05BL1	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	TP53BP2	Homo sapiens	Q05BL1	Validated Y2H	32296183
Intra	LMNB2	Q03252	POU6F2	Homo sapiens	P78424	Y2H Array	32296183
Intra	LMNB2	Q03252	POU6F2	Homo sapiens	P78424	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	LZTS1	Homo sapiens	Q9Y250	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	LZTS1	Homo sapiens	Q9Y250	Y2H Array	32296183
Intra	LMNB2	Q03252	LZTS1	Homo sapiens	Q9Y250	Validated Y2H	32296183
Intra	LMNB2	Q03252	PIBF1	Homo sapiens	Q4G0R1	Validated Y2H	32296183
Intra	LMNB2	Q03252	ZC2HC1C	Homo sapiens	Q53FD0-2	Validated Y2H	32296183
Intra	LMNB2	Q03252	ZC2HC1C	Homo sapiens	Q53FD0-2	Y2H Array	32296183
Intra	LMNB2	Q03252	ZC2HC1C	Homo sapiens	Q53FD0-2	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	AMOT	Homo sapiens	A2BDD9	Y2H Array	32296183
Intra	LMNB2	Q03252	AMOT	Homo sapiens	A2BDD9	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	EFHC2	Homo sapiens	Q5JST6	Y2H Array	32296183
Intra	LMNB2	Q03252	EFHC2	Homo sapiens	Q5JST6	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	EFHC2	Homo sapiens	Q5JST6	Validated Y2H	32296183
Intra	LMNB2	Q03252	LMNB1	Homo sapiens	P20700	Crosslink	30021884
Intra	LMNB2	Q03252	LMNA	Homo sapiens	P02545	Anti Tag CoIP	33961781
Intra	LMNB2	Q03252	LMNB1	Homo sapiens	P20700	Anti Tag CoIP	33961781
Intra	LMNB2	Q03252	CDC37	Homo sapiens	Q16543	Validated Y2H	32296183
Intra	LMNB2	Q03252	CCDC88B	Homo sapiens	A6NC98	Y2H Array	32296183
Intra	LMNB2	Q03252	CCDC88B	Homo sapiens	A6NC98	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	OVOL1	Homo sapiens	O14753	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	OVOL1	Homo sapiens	O14753	Y2H Array	32296183
Intra	LMNB2	Q03252	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	GOLGA2	Homo sapiens	Q08379	Validated Y2H	32296183
Intra	LMNB2	Q03252	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
Intra	LMNB2	Q03252	WASHC3	Homo sapiens	Q9Y3C0	Validated Y2H	32296183
Intra	LMNB2	Q03252	TRIM27	Homo sapiens	P14373	Y2H Array	32296183
Intra	LMNB2	Q03252	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	THAP1	Homo sapiens	Q9NVV9	Validated Y2H	32296183
Intra	LMNB2	Q03252	THAP1	Homo sapiens	Q9NVV9	Y2H Array	32296183
Intra	LMNB2	Q03252	THAP1	Homo sapiens	Q9NVV9	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	CCDC120	Homo sapiens	Q96HB5	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	CCDC120	Homo sapiens	Q96HB5	Validated Y2H	32296183
Intra	LMNB2	Q03252	CCDC120	Homo sapiens	Q96HB5	Y2H Array	32296183
Intra	LMNB2	Q03252	AMOTL2	Homo sapiens	Q9Y2J4	Validated Y2H	32296183
Intra	LMNB2	Q03252	AMOTL2	Homo sapiens	Q9Y2J4	Y2H Prey Pooling	32296183
Intra	LMNB2	Q03252	AMOTL2	Homo sapiens	Q9Y2J4	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

LMNB2 抗体

製品番号	製品名	アプリケーション	反応性
HY-P81283	Lamin B2 Antibody (YA989)	WB, IP	Human, Mouse
HY-P81283A	Lamin B2 Antibody (YA990)	WB	Human, Mouse, Rat
HY-P84477	Lamin B2 Antibody (YA4174)	WB, IHC-P, ICC/IF, FC, ELISA	Human
HY-P84477A	Lamin B2 Antibody (YA4174)(PBS only)	WB, IHC-P, ICC/IF, FC, ELISA	Human
HY-P85640	Lamin B2 Antibody (YA5332)	WB	Human, Mouse

関連疾患

Diseases	Alias
Epilepsy, Progressive Myoclonic, 9	EPM9 Progressive Myoclonic Epilepsy Type 9 Pme Type 9 Progressive Myoclonic Epilepsy Due To Lmnb2 Deficiency Progressive Myoclonus Epilepsy Type 9 Epilepsy, Progressive Myoclonic 9
Microcephaly 27, Primary, Autosomal Dominant	MCPH27
Lipodystrophy, Partial, Acquired	Barraquer-Simons Syndrome Acquired Partial Lipodystrophy APLD Lipodystrophy, Partial, Acquired, Susceptibility To Apl Progressive Cephalothoracic Lipodystrophy Apld, Susceptibility To Lipodystrophy, Cephalothoracic Type Lipodystrophy, Partial, Progressive Lipodystophy Partial Progressive Lipodystrophy Cephalothoracic Type Lipodystrophy Partial Acquired Partial Acquired Lipodystrophy Cephalothoracic Type Lipodystrophy Partial Progressive Lipodystrophy Susceptibility To Partial Acquired Lipodystrophy
Acquired Lipodystrophy
Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant	ADLD Adult-Onset Autosomal Dominant Demyelinating Leukodystrophy Leukodystrophy, Adult-Onset, Autosomal Dominant Adult-Onset Autosomal Dominant Leukodystrophy Autosomal Dominant Leukodystrophy With Autonomic Disease Autosomal Dominant Adult-Onset Demyelinating Leukodystrophy Multiple Sclerosis-Like Disorder Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type, Formerly Autosomal-Dominant Or Late-Onset Type Pelizaeus-Merzbacher Disease Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type Adult-Onset Autosomal Dominant Leukodystrophy With Autonomic Symptoms Lmnb1-Related Adult-Onset Autosomal Dominant Leukodystrophy Leukodystrophy, Demyelinating, Autosomal Dominant, Adult-Onset Pelizaeus-Merzbacher Disease Autosomal Dominant Pelizaeus-Merzbacher Disease Late-Onset Type Adult Onset Autosomal Dominant Leukodystrophy
Emery-Dreifuss Muscular Dystrophy	Edmd Emery-Dreifuss Syndrome Muscular Dystrophy, Emery-Dreifuss Humeroperoneal Neuromuscular Disease Muscular Dystrophy, Tardive, Dreifuss-Emery Type, With Contractures Scapuloperoneal Syndrome, X-Linked Benign Scapuloperoneal Muscular Dystrophy With Early Contractures Muscular Dystrophy, Emery-Dreifuss Type Muscular Dystrophy Emery-Dreifuss Dystrophy, Muscular, Emery-Dreifuss Emd - [Emery-Dreifuss Muscular Dystrophy]
Familial Partial Lipodystrophy	Lipodystrophy, Familial Partial Fpld Kobberling-Dunnigan Syndrome Dunnigan Syndrome Koberling-Dunnigan Syndrome Dunnigan-Kobberling Syndrome Fpl Familial Partial Lipodystrophy, Type 2
Charcot-Marie-Tooth Disease, Axonal, Type 2b1	Charcot-Marie-Tooth Disease Type 2b1 Charcot-Marie-Tooth Disease, Type 2b1 CMT2B1 Autosomal Recessive Axonal Cmt4c1 Autosomal Recessive Charcot-Marie-Tooth Disease Type 2b1 Charcot-Marie-Tooth Disease Neuronal Type 2b1 Charcot-Marie-Tooth Neuropathy Type 2b1 Charcot-Marie-Tooth Disease, Neuronal, Type 2b1 Charcot-Marie-Tooth Disease, Axonal, Autosomal Recessive, Type 2b1 Charcot-Marie-Tooth Neuropathy, Type 2b1 Autosomal Recessive Axonal Charcot-Marie-Tooth Disease Type 2b1 Ar-Cmt2b1 Charcot-Marie-Tooth Disease 2b1 Charcot-Marie-Tooth Disease Axonal Autosomal Recessive B1 Charcot-Marie-Tooth Disease Axonal Type 2b1
Lipodystrophy, Familial Partial, Type 2	FPLD2 Lipoatrophic Diabetes Familial Partial Lipodystrophy Type 2 Familial Partial Lipodystrophy, Dunnigan Type Fpl2 Lipoatrophic Diabetes Mellitus Lipodystrophy, Familial Partial, Dunnigan Type Lipodystrophy, Familial, Of Limbs And Lower Trunk Lipodystrophy, Reverse Partial Familial Partial Lipodystrophy Dunnigan Type Dunnigan Syndrome Familial Lipodystrophy Of Limbs And Lower Trunk Reverse Partial Lipodystrophy Lipodystrophy, Familial Partial, 2 Generalized Lipoatrophy Associated With Diabetes, Hepatic Steatosis, Hypertrophic Cardiomyopathy And Leukomelanodermic Papules Lipodystrophy Familial Of Limbs And Lower Trunk Lipodystrophy Reverse Partial Diabetes Mellitus, Lipoatrophic Familial Partial Lipodystrophy, Type 2 Familial Generalized Lipodystrophy
Nonencapsulated Sclerosing Carcinoma	Nonencapsulated Sclerosing Neoplasm Papillary Carcinoma, Diffuse Sclerosing
Greenberg Dysplasia	Hem Dysplasia Greenberg Skeletal Dysplasia Hem Skeletal Dysplasia GRBGD Hydrops-Ectopic Calcification-Moth-Eaten Skeletal Dysplasia Moth-Eaten Skeletal Dysplasia Chondrodystrophy, Hydropic And Prenatally Lethal Type Hydrops-Ectopic Calcification-Motheaten Syndrome Skeletal Dysplasia, Greenberg Type Autosomal Recessive Lethal Chondrodystrophy With Congenital Hydrops Hydrops, Ectopic Calcification, Moth-Eaten Skeletal Dysplasia Hem Hem/Greenberg Dysplasia Hydrops - Ectopic Calcification - Moth-Eaten Skeletal Dysplasia
Muscular Dystrophy, Congenital, Lmna-Related	Congenital Muscular Dystrophy Congenital Muscular Dystrophy Due To Lmna Mutation MDCL L-Cmd Lmna-Related Congenital Muscular Dystrophy Muscular Dystrophy, Congenital Congenital Muscular Dystrophy Lmna-Related Lmna-Related Cmd Cmd Mdc Muscular Dystrophy Congenital Lmna-Related Dystrophy, Muscular, Congenital, Lmna-Related Dystrophy, Muscular, Congenital Hereditary Muscular Dystrophy Congenital Hereditary Muscular Dystrophy Congenital Progressive Muscular Dystrophy Hereditary Progressive Muscular Dystrophy
Emery-Dreifuss Muscular Dystrophy 2, Autosomal Dominant	EDMD2 Autosomal Dominant Emery-Dreifuss Muscular Dystrophy Emd2 Emery-Dreifuss Muscular Dystrophy, Autosomal Dominant Scapuloilioperoneal Atrophy With Cardiopathy Muscular Dystrophy With Early Contractures And Cardiomyopathy, Autosomal Dominant Hauptmann-Thannhauser Muscular Dystrophy Cardiomyopathy, Dilated, With Quadriceps Myopathy Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 2 Muscular Dystrophy, Limb-Girdle, Type 1b Muscular Dystrophy, Limb-Girdle, Type 1b, Formerly Lgmd1b, Formerly Muscular Dystrophy, Proximal, Type 1b, Formerly Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1b Lgmd1b Limb-Girdle Muscular Dystrophy 1b Muscular Dystrophy, Proximal, Type 1b Muscular Dystrophy With Early Contractures And Cardiomyopathy Autosomal Dominant
Reynolds Syndrome	Primary Biliary Cirrhosis, Scleroderma, Raynaud Disease, And Telangiectasia Primary Biliary Cirrhosis And Systemic Scleroderma REYNS Primary Biliary Cirrhosis Scleroderma Raynaud Disease And Telangiectasia
Pelger-Huet Anomaly	PHA Pelger-Huët Anomaly Ovoid Neutrophil Nuclei, Developmental Delay, Epilepsy And Skeletal Abnormalities Pelger Huet Anomaly Pelger-Huet Nuclear Anomaly
Buschke-Ollendorff Syndrome	BOS Dermatoosteopoikilosis Dermatofibrosis Lenticularis Disseminata With Osteopoikilosis Osteopathia Condensans Disseminata Dermatofibrosis Lenticularis Disseminata Disseminated Dermatofibrosis With Osteopoikilosis Dermatofibrosis, Disseminated, With Osteopoikilosis Osteopoikilosis With Or Without Melorheostosis Dermatofibrosis, Disseminated With Osteopoikilosis Dermatofibrosis Disseminata Lenticularis Isolated Osteopoikilosis Osteopoikilosis, Isolated
Emery-Dreifuss Muscular Dystrophy 1, X-Linked	EDMD1 Emd1 Muscular Dystrophy, Tardive, Dreifuss-Emery Type, With Contractures X-Linked Emery-Dreifuss Muscular Dystrophy 1 Humeroperoneal Neuromuscular Disease X-Linked Emery-Dreifuss Muscular Dystrophy Scapuloperoneal Syndrome, X-Linked, Formerly Humeroperoneal Neuromuscular Disease, Formerly Scapuloperoneal Syndrome, X-Linked Muscular Dystrophy Tardive Dreifuss-Emery Type With Contractures Scapuloperoneal Syndrome X-Linked X-Edmd Dystrophy, Muscular, Emery-Dreifuss, Type 1, X-Linked
Emery-Dreifuss Muscular Dystrophy 3, Autosomal Recessive	EDMD3 Autosomal Recessive Emery-Dreifuss Muscular Dystrophy 3 Autosomal Recessive Emery-Dreifuss Muscular Dystrophy Emery-Dreifuss Muscular Dystrophy Atypical Autosomal Recessive Dystrophy, Muscular, Emery-Dreifuss, Type 3, Autosomal Recessive Emery-Dreifuss Muscular Dystrophy 3
Axonal Neuropathy
Cardiomyopathy, Dilated, 1h	Dilated Cardiomyopathy 1h Dilated Cardiomyopathy With Conduction Defect CMD1H Cardiomyopathy, Dilated, With Conduction Defect
Emery-Dreifuss Muscular Dystrophy 4, Autosomal Dominant	EDMD4 Emery-Dreifuss Muscular Dystrophy 4 With Variable Features Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 4 Emd4 Dystrophy, Muscular, Emery-Dreifuss, Type 4, Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 4
Complement Deficiency	Complement Deficiency Disease Hereditary Complement Deficiency Diseases
Muscular Dystrophy	Muscular Dystrophies Congenital Md Congenital Muscular Dystrophy Cmd Mdc Dystrophy, Muscular Gower'S Muscular Dystrophy Progressive Musclular Dystrophy Pseudohypertrophic Atrophy Pseudohypertrophic Muscle Paralysis Pseudohypertrophic Muscular Atrophy Pseudohypertrophic Muscular Dystrophy Pseudohypertrophic Paralysis Pseudomuscular Hypertrophy
Microcephaly	Microencephaly Microcephalus Microcephalic Nanocephaly Congenital Microcephaly Brain Hypoplasia Brain Nondevelopment Cephalic Hypoplasia Undeveloped Cerebrum Undeveloped Brain Micrencephalon Micrencephaly
Osteopoikilosis	Osteopathia Condensans Disseminata Spotted Bones Dermatofibrosis Lenticularis Disseminata
Epilepsy	Epilepsy Syndrome Epileptic Syndrome Epilepsies Symptomatic Epilepsies Post Traumatic Epilepsy Traumatic Epilepsy Traumatic Epileptic Epilepsy Due To Hippocampal Sclerosis Epilepsy With Ammon'S Horn Sclerosis Epilepsy Due To Cortical Dysplasia Epilepsy Due To Neuronal Migration Disorders
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Hutchinson-Gilford Progeria Syndrome	Progeria HGPS Hutchinson-Gilford Syndrome Hutchinson-Gilford Progeria Hutchinson Gilford Syndrome Hutchinson Gilford Progeria Syndrome Hutchinson-Gilford Disease Progeria Of Childhood Hutchinson-Gilford-Progeria Syndrome
Cardiomyopathy, Dilated, 1a	Dilated Cardiomyopathy 1a Cdcd1 CMD1A Cardiomyopathy, Familial Idiopathic Familial Dilated Cardiomyopathy With Conduction Defect Due To Lmna Mutation Cardiomyopathy, Dilated, With Conduction Defect 1 Cardiomyopathy, Idiopathic Dilated Cardiomyopathy, Congestive Dilated Cardiomyopathy With Conduction Defect 1 Cardiomyopathy Dilated With Conduction Defect Type 1 Cardiomyopathy, Dilated 1a Cardiomyopathy Dilated With Conduction Defect 1 Cardiomyopathy, Dilated, Type 1a
Hyperoxaluria, Primary, Type I	Primary Hyperoxaluria Type 1 HP1 Glycolic Aciduria Alanine-Glyoxylate Aminotransferase Deficiency Hepatic Agt Deficiency Oxalosis I Primary Hyperoxaluria, Type I Serine:Pyruvate Aminotransferase Deficiency Hyperoxaluria, Primary, Type 1 Peroxisomal Alanine-Glyoxylate Aminotransferase Deficiency Peroxisomal Alanine Glyoxylate Aminotransferase Deficiency Serine Pyruvate Aminotransferase Deficiency Peroxisomal Alanine:Glyoxylate Aminotransferase Deficiency Oxalosis 1 Hyperoxaluria Primary 1 Hyperoxaluria Primary Type I Ph1 Primary Hyperoxaluria Type I Oxalosis Type 1 2-Oxoglutarate Glyoxylate Carboligase Deficiency
Muscle Tissue Disease
Primary Hyperoxaluria	Hyperoxaluria Hyperoxaluria, Primary Oxalosis Primary Oxalosis Congenital Oxaluria D-Glycerate Dehydrogenase Deficiency Glyceric Aciduria Glycolic Aciduria Hepatic Agt Deficiency Oxaluria, Primary Peroxisomal Alanine:Glyoxylate Aminotransferase Deficiency Primary Oxaluria Hyperoxaluria Primary Primary Hyperoxaluria Type 2 Primary Hyperoxaluria, Type I
Muscular Disease
Limb-Girdle Muscular Dystrophy	Lgmd Limb Girdle Muscular Dystrophy Muscular Dystrophies, Limb-Girdle Erb'S Muscular Dystrophy Leyden-Mbius Muscular Dystrophy Limb-Girdle Syndrome Myopathic Limb-Girdle Syndrome Limb Girdle Muscular Dystrophy Limb-Girdle Dystrophy, Muscular, Limb-Girdle Lgmd - [Limb-Girdle Muscular Dystrophy] Limb Girdle Muscle Dystrophy Limb-Girdle Myopathy
Progressive Myoclonus Epilepsy	Pme Progressive Myoclonic Epilepsy Myoclonic Epilepsies, Progressive Unverricht-Lundborg Syndrome
Congenital Generalized Lipodystrophy	Berardinelli-Seip Congenital Lipodystrophy Berardinelli-Seip Syndrome Brunzell Syndrome Bscl Generalized Lipodystrophy Lipodystrophy, Congenital Generalized Seip Syndrome Total Lipodystrophy Cgl Lipoatrophic Diabetes Lipodystrophy, Generalized, Congenital Familial Generalized Lipodystrophy Congenital Generalized Lipodystrophy Type 2 Lipoatrophic Diabetes Mellitus Familial Partial Lipodystrophy, Type 2
Neuromuscular Disease	Neuromuscular Diseases Neuromuscular Disorders Neuromuscular Disorder
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy
Charcot-Marie-Tooth Disease	Cmt Hmsn Hereditary Motor And Sensory Neuropathy Pma Cmt - Charcot-Marie-Tooth Disease Charcot Marie Tooth Disease Charcot-Marie-Tooth Hereditary Neuropathy Charcot-Marie-Tooth Syndrome Peroneal Muscular Atrophy Hereditary Motor And Sensory Neuropathies
Myopathy	Muscular Diseases Myopathies

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS07716	LMNB2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21630	Lmnb2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28148	Lmnb2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Felis catus	LMNB2	VGNC	VGNC:68068
Macaca mulatta	LMNB2	VGNC	VGNC:74429
Mus musculus	LMNB2	MGD	MGI:96796
Bos taurus	LMNB2	VGNC	VGNC:30931
Canis familiaris	LMNB2	VGNC	VGNC:42719
Rattus norvegicus	LMNB2	RGD	RGD:1563803
Others	LMNB2	NCBI