Me-PEG4-Me
Based on 1 Customer Validation
Me-PEG4-Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.93%
- CAS 番号: 143-24-8
- 分子式: C10H22O5
- 分子量:222.28
-
保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
PROTAC Linkers アイソフォーム固有の製品をすべて表示
More
生物活性
|
PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 143-24-8
-
性状 Liquid (Density: 1.009 g/cm3 )
-
分子量 222.28
-
分子式 C10H22O5
-
Color Colorless to light yellow
-
SMILES
COCCOCCOCCOCCOC
-
別名
Tetraglyme; Me-PEG4-Me; テトラグリム
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
H2O : ≥ 100 mg/mL (449.88 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (266 KB)
-
SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.4988 mL | 22.4942 mL | 44.9883 mL | 112.4708 mL |
| 5 mM | 0.8998 mL | 4.4988 mL | 8.9977 mL | 22.4942 mL | |
| 10 mM | 0.4499 mL | 2.2494 mL | 4.4988 mL | 11.2471 mL | |
| 15 mM | 0.2999 mL | 1.4996 mL | 2.9992 mL | 7.4981 mL | |
| 20 mM | 0.2249 mL | 1.1247 mL | 2.2494 mL | 5.6235 mL | |
| 25 mM | 0.1800 mL | 0.8998 mL | 1.7995 mL | 4.4988 mL | |
| 30 mM | 0.1500 mL | 0.7498 mL | 1.4996 mL | 3.7490 mL | |
| 40 mM | 0.1125 mL | 0.5624 mL | 1.1247 mL | 2.8118 mL | |
| 50 mM | 0.0900 mL | 0.4499 mL | 0.8998 mL | 2.2494 mL | |
| 60 mM | 0.0750 mL | 0.3749 mL | 0.7498 mL | 1.8745 mL | |
| 80 mM | 0.0562 mL | 0.2812 mL | 0.5624 mL | 1.4059 mL | |
| 100 mM | 0.0450 mL | 0.2249 mL | 0.4499 mL | 1.1247 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.