1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor

alpha-Asarone (Synonyms: α-Asarone; trans-Asarone)

Cat. No.: HY-N0700
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Alpha-Asarone is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.

For research use only. We do not sell to patients.
alpha-Asarone Chemical Structure

alpha-Asarone Chemical Structure

CAS No. : 2883-98-9

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10 mM * 1 mL in DMSO $55 In-stock
1 g $50 In-stock
5 g $70 In-stock
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Description

Alpha-Asarone is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice. IC50 value: Target: In vitro: The results indicated that α-asarone significantly attenuated the LPS-stimulated increase in neuroinflammatory responses and suppressed pro-inflammatory cytokine production in BV-2 cells. Mechanistic study revealed that α-asarone?inhibited the LPS-stimulated activation via regulation of nuclear factor kappa-B by blocking degradation of inhibitor kappa B-alpha signaling in BV-2 microglial cells. [2] In vivo: The present results reveal that the acute treatment of α-asarone elicited biphasic responses on immobility such that the duration of the immobility time is significantly reduced at lower doses (15 and 20 mg/kg, i.p.) but increased at higher doses (50 and 100 mg/kg, i.p.) in the TST. Besides, α-asarone at higher doses (50 and 100 mg/kg, i.p.) significantly decreased the spontaneous locomotor activity.[1]

References
M.Wt

208.25

Formula

C₁₂H₁₆O₃

CAS No.

2883-98-9

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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alpha-Asarone
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HY-N0700
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