SC 19886
SC 19886 is an inhibitor of Aldosterone (HY-113313) synthesis. SC 19886 blocks Aldosterone-induced DNA-dependent RNA synthesis. SC 19886 can be used in studies related to primary aldosteronism[1][2].
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 22785-18-8
- 分子式: C19H26O2
- 分子量:286.41
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
SC 19886 (infused at 0.1 mM) completely inhibits spontaneous aldosterone production in perfused Rana ridibunda frog adrenal interrenal fragments, and this irreversible effect persists for at least 7 h, while it also completely blocks the stimulatory effects of ACTH and angiotensin II on aldosterone biosynthesis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 22785-18-8
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分子量 286.41
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分子式 C19H26O2
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SMILES
C[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@@]([C@H](C(CC4)=O)C)([H])C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Netchitailo P, et al. Relative inhibitory potency of five mineralocorticoid antagonists on aldosterone biosynthesis in vitro. Biochemical pharmacology. 1985 Jan 15;34(2):189-94. [Content Brief]
[2]. Porter GA, et al. The effect of a new anti-aldosterone agent SC19886 on aldosterone-stimulated transepithelial sodium transport. J Steroid Biochem. 1972 Feb;3(2):201-8. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
SC 19886 関連分類
HY-165401 関連分類
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