10025 Results for "

Endogenous

" in MedChemExpress (MCE) Product Catalog:
Products (10025)

10025 Results for "Endogenous" in MCE Product Catalog:

173
173 Publications Verification
製品番号: HY-B2176B
CAS 番号: 74804-12-9
別名: Adenosine 5'-triphosphate dimagnesium
ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation .
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173
173 Publications Verification
製品番号: HY-B2176A
CAS 番号: 51963-61-2
別名: Adenosine-5'-triphosphate disodium trihydrate
ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation .
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173
173 Publications Verification
製品番号: HY-B2176
CAS 番号: 56-65-5
別名: Adenosine 5'-triphosphate
ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice .
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170
170 Cited Publications
製品番号: HY-B0345A
CAS 番号: 987-65-5
別名: Adenosine 5'-triphosphate disodium salt; Disodium adenosine triphosphate
ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .
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167
167 Cited Publications
製品番号: HY-W010735
CAS 番号: 34369-07-8
別名: Adenosine 5'-triphosphate disodium salt hydrate
ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation .
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164
164 Cited Publications
製品番号: HY-B2176E
CAS 番号: 1476-84-2
別名: Adenosine 5'-triphosphate magnesium
ATP (Adenosine 5'-triphosphate) magnesium is a central component of energy storage and metabolism in vivo. ATP magnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP magnesium is an important endogenous signaling molecule in immunity and inflammation .
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164
164 Cited Publications
製品番号: HY-B2176C
CAS 番号: 42373-41-1
別名: Adenosine 5'-triphosphate dipotassium
ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a central component of energy storage and metabolism in vivo. ATP dipotassium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dipotassium is an important endogenous signaling molecule in immunity and inflammation .
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151
151 Cited Publications
製品番号: HY-K0013

MCE Protease and Phosphatase Inhibitor Cocktail (EDTA-Free, 10× in ddH2O) protects protein from degradation by endogenous proteases released during protein extraction and purification.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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110
110 Cited Publications
製品番号: HY-12248
CAS 番号: 1439399-58-2
純度:  99.82%
別名: CB-839
Target:  

Glutaminase Autophagy

研究分野:  

Cancer

Telaglenastat (CB-839) is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat inuduces autophagy and has antitumor activity .
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110
110 Cited Publications
製品番号: HY-12248A
CAS 番号: 1874231-60-3
別名: CB-839 hydrochloride
Target:  

Glutaminase Autophagy

研究分野:  

Cancer

Telaglenastat (CB-839) hydrochloride is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat hydrochloride selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat hydrochloride inudces autophagy and has antitumor activity .
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92
92 Cited Publications
製品番号: HY-N0322
CAS 番号: 57-88-5
Cholesterol (from animal) is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol (from animal) plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol (from animal) is also an endogenous estrogen-related receptor α (ERRα) agonist .
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88
88 Cited Publications
製品番号: HY-D0041
CAS 番号: 148504-34-1
別名: Calcein acetoxymethyl ester
Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
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87
87 Cited Publications
製品番号: HY-B0166A
CAS 番号: 134-03-2
別名: Sodium ascorbate; Sodium L-ascorbate; Vitamin C sodium salt
L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor .
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87
87 Cited Publications
製品番号: HY-B0166
CAS 番号: 50-81-7
別名: L-Ascorbate; Vitamin C
L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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64
64 Cited Publications
製品番号: HY-13426
CAS 番号: 808118-40-3
純度:  99.92%
別名: FG-4592
研究分野:  

Infection Cancer

Roxadustat is an orally active hypoxia-inducible factor prolyl-hydroxylase (PHD) inhibitor (HIF-PHI) that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin .
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56
56 Cited Publications
製品番号: HY-D0187
CAS 番号: 70-18-8
別名: GSH; γ-L-Glutamyl-L-cysteinyl-glycine
L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.
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45
45 Cited Publications
製品番号: HY-P0264
CAS 番号: 133514-43-9
別名: Avexitide
Target:  

GLP Receptor

研究分野:  

Metabolic Disease

Exendin(9-39) amide (Avexitide) is a glucagon-like peptide-1 (GLP-1) antagonist that competes with endogenous GLP-1 for binding to GLP-1 receptors, thereby antagonizing the effects of excess GLP-1 secretion. Exendin(9-39) amide can be used to study postoperative hypoglycemia (PBH) .
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45
45 Cited Publications
製品番号: HY-P0264A
CAS 番号: 2051593-46-3
別名: Avexitide acetate
Target:  

GLP Receptor

研究分野:  

Metabolic Disease

Exendin(9-39) amide (Avexitide) acetate is a glucagon-like peptide-1 (GLP-1) antagonist that competes with endogenous GLP-1 for the GLP-1R, counteracting the effects of excessive GLP-1 secretion. Exendin(9-39) amide acetate can be utilized in Postbariatric hypoglycemia (PBH) research .
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42
42 Cited Publications
製品番号: HY-100564
CAS 番号: 1441190-66-4
純度:  99.95%
別名: 2'-3'-cyclic GMP-AMP
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm .
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42
42 Cited Publications
製品番号: HY-100564A
CAS 番号: 2734858-36-5
純度:  99.63%
別名: 2'-3'-cyclic GMP-AMP sodium
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm .
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