173 Results for "

sulfonated

" in MedChemExpress (MCE) Product Catalog:
Products (173)

173 Results for "sulfonated" in MCE Product Catalog:

7
7 Cited Publications
製品番号: HY-N1370
CAS 番号: 69659-80-9
別名: Sodium Tanshinone IIA sulfonate; Tanshinone IIA sodium sulfonate
Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca 2+ entry (SOCE), and is used to treat cardiovascular disorders.
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5
5 Cited Publications
製品番号: HY-113329
CAS 番号: 543-18-0
純度:  ≥98.0%
別名: Taurocyamine
Guanidinoethyl sulfonate (Taurocyamine) is an orally available, blood-brain permeable competitive inhibitor of taurine transporters and a competitive antagonist of glycine receptors (GlyR) (IC50=565 μM). Guanidinoethyl sulfonate has both weak agonist and antagonist effects on GABAA receptors. Guanidinoethyl sulfonate inhibits taurine transmembrane transport and competitively binds to the GlyR ligand binding domain, thereby blocking glycine-mediated chloride influx, and may regulate brain pH to exert neuroprotective effects. Guanidinoethyl sulfonate can be used for neuroprotection studies of ischemic brain injury .
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4
4 Cited Publications
製品番号: HY-W583749
CAS 番号: 73606-19-6
研究分野:  

Endocrinology

6:2 Cl-PFAES is an orally effective alternative to Perfluorooctane sulfonate. 6:2 Cl-PFAES significantly inhibits the growth of zebrafish and induces reproductive toxicity. 6:2 Cl-PFAES reduces the relative weights of epididymis and testis in male BALB/c mice. 6:2 Cl-PFAES can be used in the chrome plating industry .
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3
3 Cited Publications
製品番号: HY-D1389
CAS 番号: 2419286-92-1
別名: Sulfo-Cyanine5.5 NHS ester tripotassium
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
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2
2 Cited Publications
製品番号: HY-129524
CAS 番号: 4672-49-5
純度:  ≥98.0%
Target:  

Apoptosis

研究分野:  

Inflammation/Immunology

Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs .
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2
2 Cited Publications
製品番号: HY-B1785
CAS 番号: 97-05-2
別名: Sulfosalicylic acid; Sulphosalicylic acid; Salicylsulfonic acid
Target:  

Drug Derivative

研究分野:  

Cancer

5-Sulfosalicylic acid is a sulfonated salicylic acid derivative. 5-Sulfosalicylic acid is effective against the breast cancer cell lines, with less toxicity . 5-Sulfosalicylic acid has antioxidant activities .
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2
2 Cited Publications
製品番号: HY-B0812
CAS 番号: 5965-83-3
別名: SSA dihydrate
5-Sulfosalicylic acid dihydrate is a sulfonated salicylic acid derivative. 5-Sulfosalicylic acid dihydrate is effective against the breast cancer cell line, MCF-7, with less toxicity . 5-Sulfosalicylic acid dihydrate has antioxidant activities .
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2
2 Cited Publications
製品番号: HY-W099581
CAS 番号: 14933-09-6
別名: SB3-14; DMAPS
Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
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1
1 Cited Publications
製品番号: HY-W014837
CAS 番号: 15471-17-7
別名: 3-(1-Pyridinio)-1-propanesulfonate
NDSB-201 consists of a pyridine group attached to a propane chain, which in turn is attached to a sulfonate group. This compound is commonly used as a buffer in biochemical and biological research, especially in electrophoretic applications. It maintains a stable pH in aqueous solutions and has low UV absorption, making it suitable for use in the UV spectrum. Furthermore, due to its ability to form stable complexes with DNA and other biomolecules, 3-(pyridin-1-ium-1-yl)propane-1-sulfonate has been investigated for its potential in drug delivery and genetic research.
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1
1 Cited Publications
製品番号: HY-W250727
CAS 番号: 53313-85-2
別名: 6-(p-Tolylamino)naphthalene-2-sulfonate sodium
TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively .
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1
1 Cited Publications
製品番号: HY-D0823
CAS 番号: 146368-16-3
別名: Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester
Cy3-SE (Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester) is a sulfonated cyanine dye-derived fluorescent labeling reagent with λex of about 515 nm and λem of about 568 nm. Cy3-SE can interact with the π-π stacking of biomolecules (e.g., nucleoside monophosphates, proteins), inhibiting the photoisomerization process and increasing the fluorescence quantum yield and lifetime .
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製品番号: HY-B0491A
CAS 番号: 51460-26-5
別名: AC-17
Target:  

Adrenergic Receptor

研究分野:  

Cardiovascular Disease

Carbazochrome sodium sulfonate (AC-17) is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome sodium sulfonate is an antihemorrhagic agent .
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製品番号: HY-107929
CAS 番号: 37286-92-3
別名: Poly(styrenesulfonic acid) calcium salt
Target:  

Potassium Channel

研究分野:  

Metabolic Disease

Calcium polystyrene sulfonate (Poly(styrenesulfonic acid) calcium salt) is an orally active potassium-lowering agent. Calcium polystyrene sulfonate binds potassium in the distal colon in exchange for Ca 2+. Calcium polystyrene sulfonate can be used for the research of hyperkalemia in chronic kidney disease .
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製品番号: HY-W043437
CAS 番号: 6214-18-2
別名: Isopropyl besylate
Target:  

Drug Intermediate

研究分野:  

Others

Isopropyl benzenesulfonate (Isopropyl besylate) is an aromatic sulfonate compound and also a potentially genotoxic impurity .
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製品番号: HY-109654
CAS 番号: 27503-81-7
純度:  ≥98.0%
研究分野:  

Metabolic Disease

Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
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製品番号: HY-W250153
CAS 番号: 109434-21-1
Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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製品番号: HY-W014792
CAS 番号: 22767-50-6
Sodium heptane-1-sulfonate is an ion-pairing agent that can be used as a buffer in biochemical research and HPLC .
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製品番号: HY-164090
CAS 番号: 482-67-7
Target:  

P2Y Receptor

研究分野:  

Cardiovascular Disease

Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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製品番号: HY-46846
CAS 番号: 69011-20-7
Styrene-divinylbenzene sulfonated copolymer is a cation exchange resin prepared from sulfonic acid group-containing microporous styrene/divinylbenzene (DVB) copolymer. Styrene-divinylbenzene sulfonated copolymer serves as the core matrix material for most bilirubin adsorbents. It also acts as a hydrophilic cell immobilization carrier, whose porous structure provides an ideal environment for microbial growth and biochemical reactions .
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製品番号: HY-W099575
CAS 番号: 2281-11-0
3-(Hexadecyldimethylammonio)propane-1-sulfonate is an organic compound belonging to the class of sulfonates. It is a quaternary ammonium surfactant commonly used in various industrial and laboratory applications such as the production of detergents, personal care products and pharmaceuticals. 3-(Hexadecyldimethylammonio)propane-1-sulfonate is surface active and can be used as an emulsifier, foaming agent and wetting agent. In addition, it is used as a solubilizer in protein purification and as a surfactant in chromatography.
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