53313-85-2
Chemical Structure
TNS sodium
Synonym(s): 6-(p-Tolylamino)naphthalene-2-sulfonate sodium
- CAS No.: 53313-85-2
- Formula:C17H14NNaO3S
- Molecular Weight:335.36
IUPAC Name: 3-(methoxy-d3)-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzaldehyde
InChIKey: QZZGQOXRGFDEJP-UHFFFAOYSA-M
SMILES: O=S(C1=CC=C2C=C(NC3=CC=C(C)C=C3)C=CC2=C1)(O[Na])=O
Biological Activity: TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TNS sodium | 99.97% | TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively. | ||||||||||||||||||||
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Keywords
