ZINC08438472
ZINC08438472 is a potent and selective peroxisome proliferator activated receptors-α (PPAR-α) agonist with an EC50 value of 12.1 nM. ZINC08438472 is promising for research of diabetes, hyperlipidaemia and inflammatory disorders.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 443872-20-6
- 分子式: C25H25NO8S
- 分子量:499.53
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | EC50 |
12.1 nM
Compound: ZINC08438472
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Agonist activity at GAL4-tagged PPARalpha ligand-binding domain (unknown origin) expressed in HEK293T cells incubated for 16 to 19 hrs by beta-lactamase reporter gene assay
Agonist activity at GAL4-tagged PPARalpha ligand-binding domain (unknown origin) expressed in HEK293T cells incubated for 16 to 19 hrs by beta-lactamase reporter gene assay
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[PMID: 25491112] |
化学情報
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CAS 番号 443872-20-6
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分子量 499.53
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分子式 C25H25NO8S
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SMILES
O=C(C(C/1=O)=C(NC2=CC=C(OCC)C=C2)SC1=C\C3=CC=C(OCC(O)=O)C(OC)=C3)OCC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)