17-Epiestriol

17-Epiestriol is an estrogen metabolite and a selective estrogen receptor (ER) β agonist. 17-epiestriol inhibits the mRNA and protein expression of the vascular cell adhesion molecule VCAM-1 induced by tumor necrosis factor α (TNFα). 17-epiestriol also inhibits TNFα-induced VCAM-1 expression and prevents NF-κB migration to the nucleus. 17-Epiestriol also induces the mRNA and protein expression of endothelial nitric oxide synthase.

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  • CAS No.: 1228-72-4
  • 화학식: C18H24O3
  • 분자량:288.38
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All Estrogen Receptor/ERR Isoforms

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