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Cat. No.: HY-184975

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ERK5 ligand-2

ERK5 ligand-2 is an ERK5 ligand. ERK5 ligand-2 can serve as a ligand for the target protein in the synthesis of PROTAC ERK5 degraders, such as PPM-3 (HY-149616). ERK5 ligand-2 is suitable for use in cancer research.

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CAS No.: 1234481-27-6
화학식: C₂₄H₂₇N₇O₂
분자량:445.52

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

ERK5 ligand-2 Chemical Structure

CAS No.: 1234481-27-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
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Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

ERK5

All ERK Isoforms :

Chemical Information

CAS No. 1234481-27-6
분자량 445.52
화학식 C₂₄H₂₇N₇O₂
SMILES

O=C(C1=CC=CC=C1N(C)C2=NC(NC3=CC=C(C=C3OC)N4CCNCC4)=NC=C25)N5C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Pan P, et al. Design, Synthesis, and Biological Evaluation of Proteolysis-Targeting Chimeras as Highly Selective and Efficient Degraders of Extracellular Signal-Regulated Kinase 5. J Med Chem. 2023 Oct 12;66(19):13568-13586. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
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ERK5 ligand-2

All ERK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

ERK5 ligand-2 Related Classifications

HY-184975 Related Classifications