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Cat. No.: HY-143486

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IRAK4-IN-10

IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC₅₀ of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer.

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CAS No.: 2681278-09-9
화학식: C₂₂H₂₄N₈
분자량:400.48

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

IRAK4-IN-10 Chemical Structure

CAS No.: 2681278-09-9

사이즈

가격

재고

수량

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* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

IRAK4

1.5 nM (IC₅₀)

All IRAK Isoforms :

Chemical Information

CAS No. 2681278-09-9
분자량 400.48
화학식 C₂₂H₂₄N₈
SMILES

N#CC1=CC2=C(C=C1)C3=NC=C(C4=CN(C5CCNCC5)N=N4)C(NC(C)C)=C3N2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sabnis RW. Novel Tricyclic Heteroaryl Compounds as IRAK4 Inhibitors for Treating Cancer, Autoimmune and Inflammatory Diseases. ACS Med Chem Lett. 2022 Feb 28;13(3):336-337. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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IRAK4-IN-10

All IRAK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

IRAK4-IN-10 Related Classifications

HY-143486 Related Classifications