2681278-09-9
2681278-09-9
Chemical Structure
IRAK4-IN-10
- CAS No.: 2681278-09-9
- Formula:C22H24N8
- Molecular Weight:400.48
IUPAC Name: (R)-(5-bromobenzofuran-2-yl)(1-(4-chlorophenyl)-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)methanone
InChIKey: SMMCMYVAAGAINB-UHFFFAOYSA-N
SMILES: N#CC1=CC2=C(C=C1)C3=NC=C(C4=CN(C5CCNCC5)N=N4)C(NC(C)C)=C3N2
Biological Activity: IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer[1].
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IRAK4-IN-10 | IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer. | |||||||||||||||||||||
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References
Keywords
