Ohchinolide B
Ohchinolide B is a tubulin inhibitor. Ohchinolide B inhibits microtubule polymerization (IC50=2.3 μM) and induces G2/M phase cell cycle arrest via mitochondrial apoptotic pathways. Ohchinolide B is promising for research of solid tumors (e.g., breast, lung cancer).
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- CAS No.: 71902-49-3
- 화학식: C35H44O10
- 분자량:624.72
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa S3 | IC50 |
40.5 μM
Compound: 8
|
Cytotoxicity against human HeLaS3 cells after 72 hrs by WST1 assay
Cytotoxicity against human HeLaS3 cells after 72 hrs by WST1 assay
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[PMID: 15387656] |
Chemical Information
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CAS No. 71902-49-3
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분자량 624.72
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화학식 C35H44O10
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SMILES
C[C@]12[C@@]3([H])[C@](OC[C@@]3([C@@H](C[C@@H]2OC(C)=O)OC(C)=O)C)([H])[C@H]([C@@]4([C@]1([H])CC(O[C@]5([H])C4=C([C@H](C6=COC=C6)C5)C)=O)C)OC(/C(C)=C/C)=O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ohchinolide B Related Classifications
HY-N12331 Related Classifications
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