71902-49-3
71902-49-3
Chemical Structure
Ohchinolide B
- CAS No.: 71902-49-3
- Formula:C35H44O10
- Molecular Weight:624.72
InChIKey: CSXRQWINVNDPIA-ISDWWLKNSA-N
SMILES: C[C@]12[C@@]3([H])[C@](OC[C@@]3([C@@H](C[C@@H]2OC(C)=O)OC(C)=O)C)([H])[C@H]([C@@]4([C@]1([H])CC(O[C@]5([H])C4=C([C@H](C6=COC=C6)C5)C)=O)C)OC(/C(C)=C/C)=O
Biological Activity: Ohchinolide B is a tubulin inhibitor. Ohchinolide B inhibits microtubule polymerization (IC50=2.3 μM) and induces G2/M phase cell cycle arrest via mitochondrial apoptotic pathways. Ohchinolide B is promising for research of solid tumors (e.g., breast, lung cancer)[1].
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Ohchinolide B | Ohchinolide B is a tubulin inhibitor. Ohchinolide B inhibits microtubule polymerization (IC50=2.3 μM) and induces G2/M phase cell cycle arrest via mitochondrial apoptotic pathways. Ohchinolide B is promising for research of solid tumors (e.g., breast, lung cancer). | |||||||||||||||||||||
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