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Cat. No.: HY-10833

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ROCK-IN-10

ROCK-IN-10 (compound 50) is a potent ROCK inhibitor with IC₅₀ values of 6 nM and 4 nM for ROCK1 and ROCK2, respectively. ROCK-IN-10 shows >100-fold selectivity against other kinases.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1038549-25-5
화학식: C₂₅H₂₅N₅O₃
분자량:443.50

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

ROCK-IN-10 Chemical Structure

CAS No.: 1038549-25-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

ROCK-IN-10 (compound 50) is a potent ROCK inhibitor with IC₅₀ values of 6 nM and 4 nM for ROCK1 and ROCK2, respectively. ROCK-IN-10 shows >100-fold selectivity against other kinases^[1].

All ROCK Isoforms :

Chemical Information

CAS No. 1038549-25-5
분자량 443.50
화학식 C₂₅H₂₅N₅O₃
SMILES

O=C(C1=CC=C(NC(NCC2=CC(C(NC3=CC=C4C(CNCC4)=C3)=O)=CC=C2)=O)C=C1)N
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tina Morwick, et al. Hit to lead account of the discovery of bisbenzamide and related ureidobenzamide inhibitors of Rho kinase. J Med Chem. 2010 Jan 28;53(2):759-77. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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ROCK-IN-10

High-Throughput Bioactive Compound Library

All ROCK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

ROCK-IN-10 Related Classifications

HY-10833 Related Classifications