1038549-25-5
1038549-25-5
Chemical Structure
ROCK-IN-10
- CAS No.: 1038549-25-5
- Formula:C25H25N5O3
- Molecular Weight:443.50
IUPAC Name: 3-((3-(4-carbamoylphenyl)ureido)methyl)-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide
InChIKey: SCIFUGGHOXNSJC-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(NC(NCC2=CC(C(NC3=CC=C4C(CNCC4)=C3)=O)=CC=C2)=O)C=C1)N
Biological Activity: ROCK-IN-10 (compound 50) is a potent ROCK inhibitor with IC50 values of 6 nM and 4 nM for ROCK1 and ROCK2, respectively. ROCK-IN-10 shows >100-fold selectivity against other kinases[1].
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ROCK-IN-10 | ROCK-IN-10 (compound 50) is a potent ROCK inhibitor with IC50 values of 6 nM and 4 nM for ROCK1 and ROCK2, respectively. ROCK-IN-10 shows >100-fold selectivity against other kinases. | |||||||||||||||||||||
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References
Keywords
