SC 19886
SC 19886 is an inhibitor of Aldosterone (HY-113313) synthesis. SC 19886 blocks Aldosterone-induced DNA-dependent RNA synthesis. SC 19886 can be used in studies related to primary aldosteronism[1][2].
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 22785-18-8
- 화학식: C19H26O2
- 분자량:286.41
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
All DNA/RNA Synthesis Isoforms
More
Biological Activity
SC 19886 (infused at 0.1 mM) completely inhibits spontaneous aldosterone production in perfused Rana ridibunda frog adrenal interrenal fragments, and this irreversible effect persists for at least 7 h, while it also completely blocks the stimulatory effects of ACTH and angiotensin II on aldosterone biosynthesis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 22785-18-8
-
분자량 286.41
-
화학식 C19H26O2
-
SMILES
C[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@@]([C@H](C(CC4)=O)C)([H])C3
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Netchitailo P, et al. Relative inhibitory potency of five mineralocorticoid antagonists on aldosterone biosynthesis in vitro. Biochemical pharmacology. 1985 Jan 15;34(2):189-94. [Content Brief]
[2]. Porter GA, et al. The effect of a new anti-aldosterone agent SC19886 on aldosterone-stimulated transepithelial sodium transport. J Steroid Biochem. 1972 Feb;3(2):201-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SC 19886 Related Classifications
HY-165401 Related Classifications
Powered by Bioz