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Cat. No.: HY-186209

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TACC3-IN-4

TACC3-IN-4 is a TACC3 inhibitor. TACC3 is a scaffold protein that is highly expressed in various tumors and regulates microtubule/centrosome stability via phosphorylation by Aurora A. TACC3-IN-4 inhibits the proliferation of triple-negative breast cancer cells. TACC3-IN-4 can be used for triple-negative breast cancer research.

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CAS No.: 3115244-17-9
화학식: C₂₄H₂₆N₆O
분자량:414.50

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

TACC3-IN-4 Chemical Structure

CAS No.: 3115244-17-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Aurora Kinase Isoforms :

In Vitro

TACC3-IN-4 (Compound 15) inhibits the proliferation of CAL-51 cells after 72 h, with a GI₅₀ value of 0.86 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3115244-17-9
분자량 414.50
화학식 C₂₄H₂₆N₆O
SMILES

CN1C2=CC=C(C=C2C=N1)C3=CC=NC(NC4=CN=CC(N5C[C@H](O[C@H](C5)C)C)=C4)=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Yang, et al. Tacc inhibitor compound, pharmaceutical composition, and preparation method therefor and use thereof. WO2026026956.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

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TACC3-IN-4

All Aurora Kinase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

TACC3-IN-4 Related Classifications

HY-186209 Related Classifications