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Cat. No.: HY-165309

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UK-390957

UK-390957 is a sulfonamide. UK-390957 binds to phosphatidylserine and carbonic anhydrase. UK-390957 can be used in the research of premature ejaculation.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 364321-71-1
화학식: C₁₆H₂₀N₂O₃S₂
분자량:352.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

UK-390957 Chemical Structure

CAS No.: 364321-71-1

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가격

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

UK-390957 is a sulfonamide. UK-390957 binds to phosphatidylserine and carbonic anhydrase. UK-390957 can be used in the research of premature ejaculation^[1].

All Carbonic Anhydrase Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	4 nM Compound: 20	Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells	[PMID: 18782666]

Chemical Information

CAS No. 364321-71-1
분자량 352.47
화학식 C₁₆H₂₀N₂O₃S₂
SMILES

O=S(C1=CC=C(OC2=CC=C(SC)C=C2)C(CN(C)C)=C1)(N)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Andrews M D, et al. The Discovery of UK-390957: the Challenge of Targeting a Short Half-life, Rapid Tmax SSRI. 2010.

[2]. Small H, et al. Measurement of binding of basic drugs to acidic phospholipids using surface plasmon resonance and incorporation of the data into mechanistic tissue composition equations to predict steady-state volume of distribution. Drug Metab Dispos. 2011 Oct;39(10):1789-93. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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UK-390957

All Carbonic Anhydrase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

UK-390957 Related Classifications

HY-165309 Related Classifications