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Cat. No.: HY-142954

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UNC6212 (Kme2)

UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K_D for CBX5 of 5.7 μM.

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화학식: C₃₉H₅₃N₇O₁₁
분자량:795.88

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

UNC6212 (Kme2) Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K_D for CBX5 of 5.7 μM^[1].

All Epigenetic Reader Domain Isoforms :

Chemical Information

분자량 795.88
화학식 C₃₉H₅₃N₇O₁₁
SMILES

O=C(C1=COC=C1)NC([C@@H](O)C2=CC=CC=C2)C(N[C@@H](C)C(N[C@@H](CC3=CC=C(OC)C(OC)=C3)C(N[C@H](C(N[C@@H](CO)C(N)=O)=O)CCCCN(C)C)=O)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kean KM, et al. Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding. J Med Chem. 2022;65(3):2646-2655. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
순도&문서
References

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UNC6212 (Kme2)

All Epigenetic Reader Domain Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

UNC6212 (Kme2) Related Classifications

HY-142954 Related Classifications