1. Phenylpropanoids
  2. Methyl (E)-cinnamate

Methyl (E)-cinnamate (Synonyms: Methyl (E)-3-phenylpropenoate)

Cat. No.: HY-W067056
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Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry.

For research use only. We do not sell to patients.

Methyl (E)-cinnamate Chemical Structure

Methyl (E)-cinnamate Chemical Structure

CAS No. : 1754-62-7

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Description

Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry[1].

In Vitro

Methyl (E)-cinnamate (0~30 μM; 24 hours; MC3T3-E1 cells) significantly increases the cleaved forms of poly (ADP-ribose) polymerase (PARP) and caspase-3, while it decreases the expression levels of Survivin and Bcl-2, and significantly increases TUNEL-positive and DAPI-stained cells[1].
Methyl (E)-cinnamate (0~30 μM;7 days; MC3T3-E1 cells) suppresses the osteoblast differentiation[1].
Methyl (E)-cinnamate (1~100 μM; 24 and 48 hours; MC3T3-E1 cells) decreases cell survival and induces morphological changes. EMC decreases MAPKs signaling and cell migration[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: MC3T3-E1 cells
Concentration: 0~30 μM
Incubation Time: 24 hours
Result: Significantly increased the cleaved forms of poly (ADP-ribose) polymerase (PARP) and caspase-3, while it decreased the expression levels of Survivin and Bcl-2.

Apoptosis Analysis[1]

Cell Line: MC3T3-E1 cells
Concentration: 0~30 μM
Incubation Time: 24 hours
Result: Significantly increased TUNEL-positive and DAPI-stained cells.

Cell Differentiation Assay[1]

Cell Line: MC3T3-E1 cells
Concentration: 0~30 μM
Incubation Time: 7 days
Result: Suppressed the osteoblast differentiation.
Molecular Weight

162.19

Formula

C₁₀H₁₀O₂

CAS No.
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Methyl (E)-cinnamate
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