32 Results for "

il-13r

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "il-13r" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99025
CAS No.: 953400-68-5
Synonyms: TNX-650; MilR1444A; RG3637

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .
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1
1 Cited Publications
Cat. No.: HY-P99496
CAS No.: 2151032-62-9
Synonyms: RPC 4046; ABT 308; CC-93538

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC50s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) .
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Cat. No.: HY-126360
CAS No.: 15646-46-5
Purity:  ≥98.0%
Research Areas:  

Inflammation/Immunology

Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins .
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Cat. No.: HY-P99417
CAS No.: 2043952-59-4
Synonyms: UCB4144; VR 942

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Abrezekimab (UCB4144; VR 942) is a humanized, high-affinity, neutralizing anti-human-IL-13 antibody fragment that binds to IL-13. Abrezekimab prevents IL-13 binding to the IL-13 Rα1 subunit. Abrezekimab can be used for the research of asthma .
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Cat. No.: HY-P11147
CAS No.: 2319573-67-4
Research Areas:  

Cancer

IL13Rα2 D1 is an effective IL-13/IL13Rα2 signaling axis inhibitor. IL13Rα2 D1 can inhibit IL-13-induced cell adhesion, migration, invasion, and proliferation. IL13Rα2 D1 can inhibit FAK, Src, AKT, ERK1/2 phosphorylation, and MMP expression. IL13Rα2 D1 can be used for research on cancers such as colorectal cancer .
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Cat. No.: HY-P703974
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD213a2; il-13 R alpha 2; il13BP; il13r; il13rA2; il-13r subunit alpha-2; il-13ra2
Species:  
Source:  
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Cat. No.: HY-P78698
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: il13rA2; CD213A2; CT19; il-13r; il13BP
Species:  
Source:  
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Cat. No.: HY-P75829
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r
Species:  
Source:  
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Cat. No.: HY-P75831
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r
Species:  
Source:  
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Cat. No.: HY-P75834
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r
Species:  
Rat
Source:  
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Cat. No.: HY-P75827
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r
Species:  
Source:  
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Cat. No.: HY-P75832
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r
Species:  
Source:  
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Cat. No.: HY-P75833
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r
Species:  
Rat
Source:  
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Cat. No.: HY-P75830
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r
Species:  
Source:  
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Cat. No.: HY-P705123
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: il-13 R alpha 1; il13r; il13rA; CT19; il13rA1; NR4; CD213A1; AI882074
Species:  
Source:  
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Cat. No.: HY-P78163
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: il-13 R alpha 1; il13r; il13rA; CT19; il13rA1; NR4; CD213A1; AI882074
Species:  
Source:  
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Cat. No.: HY-P72594
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-13 receptor subunit alpha-1; il-13r-alpha-1; il-13rA1; CT19; CD213a1; il13r
Species:  
Source:  
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Cat. No.: HY-RS06689
Research Areas:  

Others

IL13RA2 Human Pre-designed siRNA Set A contains three designed siRNAs for IL13RA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P81879
Synonyms: il13rA1; il13r; il13rA; Interleukin-13 receptor subunit alpha-1; il-13 receptor subunit alpha-1; il-13r subunit alpha-1; il-13r-alpha-1; il-13rA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P704215
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: il13rA2; LCD213A2; LCT19; Lil-13r; Lil13BP
Species:  
Source:  
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