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Results for "

il-13r

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Interleukin Related (6) Akt (1) ERK (1) FAK (1) MMP (1) Small Interfering RNA (siRNA) (1) Src (1) TNF Receptor (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (5) Neurological Disease (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: Interleukin Related IRAK Itk

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-126360

Oxazolone	TNF Receptor Interleukin Related	Inflammation/Immunology
Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins .

HY-P99025

Lebrikizumab 1 Publications Verification TNX-650; MilR1444A; RG3637	Interleukin Related	Neurological Disease Inflammation/Immunology
Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to *IL-13* in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the *IL-13* driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .

HY-P99496

Cendakimab 1 Publications Verification RPC 4046; ABT 308; CC-93538	Interleukin Related	Inflammation/Immunology
Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the *IL-13* molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC₅₀s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) .

HY-P99417

Abrezekimab UCB4144; VR 942	Interleukin Related	Inflammation/Immunology
Abrezekimab (UCB4144; VR 942) is a humanized, high-affinity, neutralizing anti-human-IL-13 antibody fragment that binds to IL-13. Abrezekimab prevents IL-13 binding to the IL-13 Rα1 subunit. Abrezekimab can be used for the research of asthma .

HY-P11147

IL13Rα2 D1	Interleukin Related FAK Src Akt ERK MMP	Cancer
IL13Rα2 D1 is an effective IL-13/IL13Rα2 signaling axis inhibitor. IL13Rα2 D1 can inhibit IL-13-induced cell adhesion, migration, invasion, and proliferation. IL13Rα2 D1 can inhibit FAK, Src, AKT, ERK1/2 phosphorylation, and MMP expression. IL13Rα2 D1 can be used for research on cancers such as colorectal cancer .

HY-RS06689

IL13RA2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL13RA2 Human Pre-designed siRNA Set A contains three designed siRNAs for IL13RA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL13RA2 Human Pre-designed siRNA Set A IL13RA2 Human Pre-designed siRNA Set A

HY-P992034

APG808 PR001	Interleukin Related	Inflammation/Immunology
APG808 is an anti-human IL-4Rα monoclonal antibody. APG808 binds to IL-4Rα, prevents IL-13Rα1/IL-4Rα heterodimer formation, and disrupts *IL-13* and IL-4 mediated signaling. APG808 ablates Fc and complement effector functions. APG808 can be used for the research of chronic obstructive pulmonary disease, asthma, atopic dermatitis .

Cat. No.	Product Name	Target	Research Area

HY-P11147

IL13Rα2 D1	Interleukin Related FAK Src Akt ERK MMP	Cancer
IL13Rα2 D1 is an effective IL-13/IL13Rα2 signaling axis inhibitor. IL13Rα2 D1 can inhibit IL-13-induced cell adhesion, migration, invasion, and proliferation. IL13Rα2 D1 can inhibit FAK, Src, AKT, ERK1/2 phosphorylation, and MMP expression. IL13Rα2 D1 can be used for research on cancers such as colorectal cancer .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99025

Lebrikizumab 1 Publications Verification TNX-650; MilR1444A; RG3637	Interleukin Related	Neurological Disease Inflammation/Immunology
Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to *IL-13* in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the *IL-13* driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .

HY-P99496

Cendakimab 1 Publications Verification RPC 4046; ABT 308; CC-93538	Interleukin Related	Inflammation/Immunology
Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the *IL-13* molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC₅₀s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) .

HY-P99417

Abrezekimab UCB4144; VR 942	Interleukin Related	Inflammation/Immunology
Abrezekimab (UCB4144; VR 942) is a humanized, high-affinity, neutralizing anti-human-IL-13 antibody fragment that binds to IL-13. Abrezekimab prevents IL-13 binding to the IL-13 Rα1 subunit. Abrezekimab can be used for the research of asthma .

HY-P992034

APG808 PR001	Interleukin Related	Inflammation/Immunology
APG808 is an anti-human IL-4Rα monoclonal antibody. APG808 binds to IL-4Rα, prevents IL-13Rα1/IL-4Rα heterodimer formation, and disrupts *IL-13* and IL-4 mediated signaling. APG808 ablates Fc and complement effector functions. APG808 can be used for the research of chronic obstructive pulmonary disease, asthma, atopic dermatitis .

Species:	Human (8) Rhesus Macaque (1) Rat (3) Mouse (6) Cynomolgus (1) Canine (2)
Tag:	His (14) Avi (4) Fc (8)
Source:	HEK293 (21)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P703974

	IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His, Avi) CD213a2; il-13 R alpha 2; il13BP; il13r; il13rA2; il-13r subunit alpha-2; il-13ra2	Human	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His, Avi) is the recombinant human-derived IL-13R alpha 2 protein, expressed by HEK293, with C-Avi and C-His labeled tag.

HY-P78698

	IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His) il13rA2; CD213A2; CT19; il-13r; il13BP	Rhesus Macaque	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His) is 315 a.a., with molecular weight of 45-55 kDa.

HY-P75829

	IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r	Human	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75831

	IL-13R alpha 2 Protein, Mouse (HEK293, His-Fc) Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r	Mouse	HEK293
	IL-13R alpha 2 Protein, acting as a monomer, displays a strong binding affinity for interleukin-13 (IL-13). IL-13R alpha 2 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

HY-P75834

	IL-13R alpha 2 Protein, Rat (HEK293, His) Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r	Rat	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits strong affinity for binding to interleukin-13 (IL-13), thereby playing a crucial role in mediating the biological effects of IL-13 and regulating various cellular processes. IL-13R alpha 2 Protein, Rat (HEK293, His) is the recombinant rat-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75827

	IL-13R alpha 2 Protein, Human (HEK293, His) Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r	Human	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Human (HEK293, His) is the recombinant human-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75832

	IL-13R alpha 2 Protein, Mouse (HEK293, His) Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r	Mouse	HEK293
	The IL-13R alpha 2 protein is a high-affinity receptor for interleukin 13 (IL-13) that acts as a decoy receptor and does not induce signaling upon IL-13 binding. Mice lacking this protein exhibit increased serum immunoglobulins, interferon gamma production, and bone marrow macrophage progenitor cell frequencies. IL-13R alpha 2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75833

	IL-13R alpha 2 Protein, Rat (HEK293, Fc) Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r	Rat	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits strong affinity for binding to interleukin-13 (IL-13), thereby playing a crucial role in mediating the biological effects of IL-13 and regulating various cellular processes. IL-13R alpha 2 Protein, Rat (HEK293, Fc) is the recombinant rat-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75830

	IL-13R alpha 2 Protein, Mouse (HEK293, Fc) Interleukin-13 receptor subunit alpha-2; il-13r-alpha-2; il-13rA2; CD213a2; il13rA2; il13r	Mouse	HEK293
	IL-13R alpha 2 Protein, acting as a monomer, displays a strong binding affinity for interleukin-13 (IL-13). IL-13R alpha 2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-mFc labeled tag.

HY-P705123

	IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, Fc-Avi) il-13 R alpha 1; il13r; il13rA; CT19; il13rA1; NR4; CD213A1; AI882074	Human	HEK293

HY-P78163

	IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, His-Avi) il-13 R alpha 1; il13r; il13rA; CT19; il13rA1; NR4; CD213A1; AI882074	Human	HEK293
	The IL13RA1 protein is critical in immune signaling and binds with low affinity to IL13. It binds to IL4RA to form a functional IL13 receptor for cellular responses. IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

HY-P72594

	IL-13R alpha 1 Protein, Human (HEK293, His) Interleukin-13 receptor subunit alpha-1; il-13r-alpha-1; il-13rA1; CT19; CD213a1; il13r	Human	HEK293
	The IL13RA1 protein is critical in immune signaling and binds with low affinity to IL13. It binds to IL4RA to form a functional IL13 receptor for cellular responses. IL-13R alpha 1 Protein, Human (HEK293, His) is the recombinant human-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P704215

	*FITC-Labeled IL-13R* alpha 2 Protein, Human (HEK293, His)** il13rA2; LCD213A2; LCT19; Lil-13r; Lil13BP	Human	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. FITC-Labeled IL-13R alpha 2 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled IL-13R alpha 2 protein, expressed by HEK293, with C-His labeled tag.

HY-P76417

	IL-13R alpha 1 Protein, Rat (HEK293, Fc) Interleukin-13 receptor subunit alpha-1; il-13r-alpha-1; il-13rA1; CT19; CD213a1; il13r	Rat	HEK293
	Interleukin 13 receptor subunit alpha 1 is a subunit of the interleukin 13 receptor. Interleukin 13 receptor subunit alpha 1 has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL-13R alpha 1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77403

	IL-13R alpha 1 Protein, Cynomolgus (HEK293, His) Interleukin-13 receptor subunit alpha-1; il-13r-alpha-1; il-13rA1; CT19; CD213a1; il13r	Cynomolgus	HEK293
	The IL-13R α 1 protein binds to IL13 with low affinity and, when combined with IL4RA, forms a functional IL13 receptor. It also functions together with IL4RA as an alternative accessory protein for IL4 signaling. IL-13R alpha 1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P705721

	*IL-4R alpha & IL-13R* alpha 1 Protein, Human (HEK293, Fc)** il-4R alpha & il-13 R alpha 1; il4RA & il13rA1	Human	HEK293

HY-P76990

	IL-13R alpha 2 Protein, Canine (HEK293, His) Interleukin-13 receptor subunit alpha-1; il-13rA1; NR4; CD213a1	Canine	HEK293
	The IL-13R α2 protein is a receptor for interleukin 13 (IL-13), a signaling molecule involved in immune responses. By binding to IL-13, the IL-13R α2 protein is thought to regulate IL-13-mediated immune responses and may serve as a therapeutic target for diseases associated with IL-13 dysregulation. IL-13R alpha 2 Protein, Canine (HEK293, His) is the recombinant canine-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76989

	IL-13R alpha 2 Protein, Canine (HEK293, Fc) Interleukin-13 receptor subunit alpha-1; il-13rA1; NR4; CD213a1	Canine	HEK293
	The IL-13R α2 protein is a receptor for interleukin 13 (IL-13), a signaling molecule involved in immune responses. By binding to IL-13, the IL-13R α2 protein is thought to regulate IL-13-mediated immune responses and may serve as a therapeutic target for diseases associated with IL-13 dysregulation. IL-13R alpha 2 Protein, Canine (HEK293, Fc) is the recombinant canine-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P78699

	IL-13R alpha 1 Protein, Mouse (HEK293, His) il13rA1; CD213A1; il-13ra; NR4; RP13-128O4.2; il13rα1	Mouse	HEK293
	The IL-13R alpha 1 protein forms a receptor for interleukin-13 when it complexes with IL4RA, activating pathways in allergy response and bronchial asthma. It exhibits ubiquitous expression, including in large intestine adult, colon adult, and 27 other tissues. IL-13R alpha 1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72381

	IL-13R alpha 1 Protein, Mouse (Biotinylated, HEK293, Avi-His) Interleukin-13 receptor subunit alpha-1; il-13rA1; Interleukin-13-binding protein; Novel cytokine receptor 4; NR4; CD213a1	Mouse	HEK293
	The IL-13R α 1 protein binds to IL13 with low affinity and, when combined with IL4RA, forms a functional IL13 receptor. It also functions together with IL4RA as an alternative accessory protein for IL4 signaling. IL-13R alpha 1 Protein, Mouse (Biotinylated, HEK293, Avi-His) is the recombinant mouse-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.

HY-P70196

	IL-13R alpha 1 Protein, Mouse (HEK293, Fc) rMuInterleukin-13 receptor subunit alpha-1/il-13rA1, Fc; Interleukin-13 receptor subunit alpha-1; il-13rA1; Interleukin-13-binding protein; Novel cytokine receptor 4; NR4; CD213a1	Mouse	HEK293
	The IL-13R α 1 protein binds to IL13 with low affinity and, when combined with IL4RA, forms a functional IL13 receptor. It also functions together with IL4RA as an alternative accessory protein for IL4 signaling. IL-13R alpha 1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-hFc labeled tag.

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Source
Tag
Accession
Gene ID
Molecular Weight
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Free Sample	Yes No
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Host:	Rabbit (2)
Reactivity:	Human (2)
Application:	WB (1) FC (1) ELISA (1)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2) Biotin (5)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81879

	IL-13 Receptor alpha 1 Antibody (YA1624) il13rA1; il13r; il13rA; Interleukin-13 receptor subunit alpha-1; il-13 receptor subunit alpha-1; il-13r subunit alpha-1; il-13r-alpha-1; il-13rA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1	WB	Human
	IL-13 Receptor alpha 1 Antibody (YA1624) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-13 Receptor alpha 1.

HY-P81632

	IL-13 Receptor alpha 1 Antibody (YA1377) il13rA1; il13r; il13rA; Interleukin-13 receptor subunit alpha-1; il-13 receptor subunit alpha-1; il-13r subunit alpha-1; il-13r-alpha-1; il-13rA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1	FC, ELISA	Human
	IL-13 Receptor alpha 1 Antibody (YA1377) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-13 Receptor alpha 1.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS06689

IL13RA2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
IL13RA2 Human Pre-designed siRNA Set A contains three designed siRNAs for IL13RA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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