2. Recombinant Proteins
  3. Cytokines and Growth Factors Receptor Proteins Biotinylated Proteins
  4. Interleukin & Receptors Cytokine Receptors
  5. IL-13 Receptor
  6. IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His)

IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His)

Cat. No.: HY-P75829
Handling Instructions

IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) is 316 a.a., with molecular weight of ~38 kDa.

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Description

IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) is 316 a.a., with molecular weight of ~38 kDa.
Background

The IL-13R alpha 2 protein functions as a monomer with high affinity, specifically binding to interleukin-13 (IL13) but not to interleukin-4 (IL4). This selectivity in binding suggests a distinct role and specificity for IL-13R alpha 2 in mediating responses to IL13, highlighting its importance in cellular processes associated with this cytokine.
Species

Human
Source

HEK293
Tag

C-His
Accession

Q14627/NP_000631.1 (D27-L342)
Gene ID
Molecular Construction
N-term
IL-13Rα2 (M1-L342)
Accession # Q14627
His
C-term
Synonyms
Interleukin-13 receptor subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13RA2; IL13R
Molecular Weight

Approximately 38 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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