5-OH-Tryptophane in migraine: clinical and neurophysiological considerations

  • J Neurol. 1981;225(1):41-6. doi: 10.1007/BF00313460.
A Boiardi ,  P Crenna ,  B Merati ,  S Negri ,  E Tansini ,  G Bussone
PMID: 6164755 DOI: 10.1007/BF00313460
Abstract

The clinical effects of the protracted treatment with 5-OH Tryptophane (5-HTP) of some patients with chronic migraine are compared with Other patients with acetylsalicylic acid. The pain threshold was neurophysiologically determined in migraneous on patients whose response to 5-HTP therapy was specially good. The results with 5-HTP can be accounted for by an action of the substance on the serotonin turnover with activation of the serotoninergic antinociceptive system.

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