1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-5-Hydroxytryptophan

L-5-Hydroxytryptophan (Synonyms: L-5-HTP; Oxitriptan)

Cat. No.: HY-B1716 Purity: 99.75%
Handling Instructions

L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia.

For research use only. We do not sell to patients.

L-5-Hydroxytryptophan Chemical Structure

L-5-Hydroxytryptophan Chemical Structure

CAS No. : 4350-09-8

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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  • Biological Activity

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Description

L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5].

IC50 & Target

Human Endogenous Metabolite

 

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (454.09 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5409 mL 22.7046 mL 45.4091 mL
5 mM 0.9082 mL 4.5409 mL 9.0818 mL
10 mM 0.4541 mL 2.2705 mL 4.5409 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (11.35 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (11.35 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

220.22

Formula

C₁₁H₁₂N₂O₃

CAS No.

4350-09-8

SMILES

N[[email protected]@H](CC1=CNC2=CC=C(O)C=C12)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
L-5-Hydroxytryptophan
Cat. No.:
HY-B1716
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L-5-Hydroxytryptophan

Cat. No.: HY-B1716