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RO5256390 

Cat. No.: HY-12700
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RO5256390 is an agonist of trace amine-associated receptor 1 (TAAR1), a highly conserved G-protein-coupled receptor (GPCR) bound by endogenous trace amines. RO5256390 can be used to reduce multiple behavioral effects of drugs of abuse through their actions on the mesocorticolimbic system. RO5256390 is a modulator of monoaminergic neurotransmission, blocks psychostimulant-induced hyperactivity and produces a brain activation pattern reminiscent of the antipsychotic drug olanzapine, suggesting antipsychotic-like properties.

For research use only. We do not sell to patients.

RO5256390 Chemical Structure

RO5256390 Chemical Structure

CAS No. : 1043495-96-0

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Description

RO5256390 is an agonist of trace amine-associated receptor 1 (TAAR1), a highly conserved G-protein-coupled receptor (GPCR) bound by endogenous trace amines. RO5256390 can be used to reduce multiple behavioral effects of drugs of abuse through their actions on the mesocorticolimbic system[1]. RO5256390 is a modulator of monoaminergic neurotransmission, blocks psychostimulant-induced hyperactivity and produces a brain activation pattern reminiscent of the antipsychotic drug olanzapine, suggesting antipsychotic-like properties[2].

Molecular Weight

218.29

Formula

C₁₃H₁₈N₂O

CAS No.

1043495-96-0

SMILES

NC1=N[[email protected]@H](C[[email protected]@H](C2=CC=CC=C2)CC)CO1

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Please store the product under the recommended conditions in the Certificate of Analysis.

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RO5256390
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HY-12700
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