2. (S)-Remoxipride

(S)-Remoxipride  (Synonyms: (-)-Remoxipride)

Cat. No.: HY-101313
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(S)-Remoxipride ((-)-Remoxipride) is a selective dopamine D2-receptor antagonist with an IC50 value of 1.57 μM. (S)-Remoxipride can be used for the research of psychotic disorder.

For research use only. We do not sell to patients.

(S)-Remoxipride Chemical Structure

(S)-Remoxipride Chemical Structure

CAS No. : 80125-14-0

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(S)-Remoxipride Related Antibodies

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Description

(S)-Remoxipride ((-)-Remoxipride) is a selective dopamine D2-receptor antagonist with an IC50 value of 1.57 μM. (S)-Remoxipride can be used for the research of psychotic disorder[1].
In Vitro

(S)-Remoxipride (1-100 μM; 20 min) shows binding efficiency with IC50s of ＞100, 1.57 and 42 μM for dopamine D1, dopamine D2 and α1-Adrenoccptor, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(S)-Remoxipride Related Antibodies
In Vivo

(S)-Remoxipride (0.1-100 μM/kg; i.p. 60 min prior to apomorphine) blockades apomorphine-induced behaviors s in rats and vomiting in dogs[1].
(S)-Remoxipride (0.1-10 mg/kg; i.p. 30 min prior to apomorphine) displaces [3H]spiperone from both striatal and extra-striatal areas[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats[1]
Dosage: 0.1-100 μM/kg
Administration: Intraperitoneal injection; 0.1-100 μM/kg; 60 min prior to apomorphine
Result: Blocked apomorphine-induced hyperactivity and dose-dependent blockaded apomorphine-induced behaviors in vivo.
Animal Model: Male and female beagle dogs[1]
Dosage: 0.25-5 μM/kg
Administration: Oral gavage; 0.25-5 μM/kg; 60 min prior to apomorphine
Result: Blocked apomorphine-induced vomiting in dogs.
Molecular Weight

371.27

Formula

C16H23BrN2O3
CAS No.
SMILES

O=C(NC[C@H]1N(CC)CCC1)C2=C(OC)C=CC(Br)=C2OC
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-Remoxipride80125-14-0(-)-RemoxiprideInhibitorinhibitorinhibit

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