2. Cell Cycle/DNA Damage TGF-beta/Smad Stem Cell/Wnt Cytoskeleton
  3. ROCK
  4. Scaff10-8

Scaff10-8, bound to RhoA, inhibits the AKAP-Lbc-mediated RhoA activation.

For research use only. We do not sell to patients.

Scaff10-8

Scaff10-8 Chemical Structure

CAS No. : 777857-56-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
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Based on 1 publication(s) in Google Scholar

Scaff10-8 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Scaff10-8

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Description

Scaff10-8, bound to RhoA, inhibits the AKAP-Lbc-mediated RhoA activation[1].

Molecular Weight

378.37

Formula

C22H18O6
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(CCC1=C(C2=CC3=C(C=C2OC1=O)OC=C3C4=CC=C(C=C4)OC)C)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (264.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6429 mL 13.2146 mL 26.4292 mL
5 mM 0.5286 mL 2.6429 mL 5.2858 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6429 mL 13.2146 mL 26.4292 mL 66.0729 mL
5 mM 0.5286 mL 2.6429 mL 5.2858 mL 13.2146 mL
10 mM 0.2643 mL 1.3215 mL 2.6429 mL 6.6073 mL
15 mM 0.1762 mL 0.8810 mL 1.7619 mL 4.4049 mL
20 mM 0.1321 mL 0.6607 mL 1.3215 mL 3.3036 mL
25 mM 0.1057 mL 0.5286 mL 1.0572 mL 2.6429 mL
30 mM 0.0881 mL 0.4405 mL 0.8810 mL 2.2024 mL
40 mM 0.0661 mL 0.3304 mL 0.6607 mL 1.6518 mL
50 mM 0.0529 mL 0.2643 mL 0.5286 mL 1.3215 mL
60 mM 0.0440 mL 0.2202 mL 0.4405 mL 1.1012 mL
80 mM 0.0330 mL 0.1652 mL 0.3304 mL 0.8259 mL
100 mM 0.0264 mL 0.1321 mL 0.2643 mL 0.6607 mL
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Scaff10-8 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Scaff10-8777857-56-4ROCKRho-associated protein kinaseRho-associated kinaseRho-kinaseROKrenal principal cellrenal inner medullary collecting duct principal cellInhibitorinhibitorinhibit

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