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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
7-MAD-MDCPT
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "7-MAD-MDCPT" in MCE Product Catalog:
Target:
Research Areas:
7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) .
Research Areas:
Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a agent-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make an antibody agent conjugate (ADC), ABBV-969 .
Target:
Research Areas:
NH2-bicyclopentane-7-MAD-MDCPT (Formula I) is a topoisomerase I (TOP1) inhibitor. NH2-bicyclopentane-7-MAD-MDCPT is applicable to the synthesis of the ADC ABBV-969. NH2-bicyclopentane-7-MAD-MDCPT is used in research on lung adenocarcinoma and melanoma .
Cat. No.: HY-164367
CAS No.: 2396667-62-0
Target:
Research Areas:
Mal-Bal-Ph(β-D-Glucose)-7-MAD-MDCPT (example 70) is an ADC drug-linker conjugate composed of the Camptothecin analog 7-MAD-MDCPT (HY-132162), and a Mal-Bal-Ph(β-D-Glucose) linker. DBCO-PEG2-C2-acid can be used to synthesize antibody-drug conjugates (ADCs) .
Cat. No.: HY-171945
CAS No.: 2850366-99-1
Synonyms: ABBV-400; Temab-A
Research Areas:
Telisotuzumab Adizutecan (ABBV-400) is an anti-c-Met antibody-drug conjugate (ADC). Telisotuzumab Adizutecan is composed of the humanized anti-c-Met antibody Telisotuzumab (HY-P99391) and the topoisomerase 1 inhibitor (7-MAD-MDCPT) (HY-132162). Telisotuzumab Adizutecan exhibits significant anti-tumor activity against advanced solid tumors such as colorectal cancer, gastric cancer, and non-small cell lung cancer .
Cat. No.: HY-148819A
Purity: 98.46%
Target:
Research Areas:
NH2-bicyclopentane-7-MAD-MDCPT hydrochloride (Formula I) is a topoisomerase I (TOP1) inhibitor. NH2-bicyclopentane-7-MAD-MDCPT hydrochloride is applicable to the synthesis of the ADC ABBV-969. NH2-bicyclopentane-7-MAD-MDCPT hydrochloride is used in research on lung adenocarcinoma and melanoma .
Cat. No.: HY-132162A
CAS No.: 2740593-09-1
Target:
Research Areas:
7-MAD-MDCPT hydrochloride, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) .
Cat. No.: HY-132162B
CAS No.: 2378428-15-8
Target:
Research Areas:
7-MAD-MDCPT TFA, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) .
Cat. No.: HY-132164
CAS No.: 2378427-68-8
Target:
Research Areas:
Gly-7-MAD-MDCPT (compound 4b) is an anticancer agent. Gly-7-MAD-MDCPT is a Camptothecin (HY-16560) compound, it shows cytotoxicity to various cancer cells with IC50 values of 10-1000 nM .
Cat. No.: HY-132164B
Target:
Research Areas:
Gly-7-MAD-MDCPT (Compound 4b) TFA is an anticancer agent. Gly-7-MAD-MDCPT TFA is a Camptothecin (HY-16560) compound, which shows cytotoxicity to various cancer cells with IC50 values of 10-1000 nM .
Cat. No.: HY-145943
CAS No.: 2639190-44-4
Target:
Research Areas:
MP-PEG8-Val-Lys-Ala-7-MAD-MDCPT is a agent-linker conjugate for antibody-drug conjugate (ADC). MP-PEG8-Val-Lys-Ala-7-MAD-MDCPT has the potential for cancer and autoimmune disease research.
Target:
Research Areas:
MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a Camptothecin-linker compound extracted from patent WO2019195665A1, example 4-1. MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a agent-linker conjugate for antibody-drug conjugate (ADC) .
Cat. No.: HY-179204
CAS No.: 2911575-71-6
Target:
Research Areas:
7-MAD-MDCPT-AC-(s-cyclopropane) is a derivative of camptothecin. 7-MAD-MDCPT-AC-(s-cyclopropane) can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. 7-MAD-MDCPT-AC-(s-cyclopropane) can be used for cancer research .
Cat. No.: HY-132164A
Target:
Research Areas:
Gly-7-MAD-MDCPT (Compound 4b) hydrochloride is an anticancer agent. Gly-7-MAD-MDCPT hydrochloride is a Camptothecin (HY-16560) compound, which shows cytotoxicity to various cancer cells with IC50 values of 10-1000 nM .
Cat. No.: HY-175272
Research Areas:
DBCO-PEG8-VKG-CPT2 is a drug-linker conjugate for ADC. DBCO-PEG8-VKG-CPT2 consists of a topoisomerase 1 inhibitor (7-MAD-MDCPT) (HY-132162) and a stable and cleavable linker (DBCO-PEG8-VKG) (HY-175426). DBCO-PEG8-VKG-CPT2 can be used for synthesis of ADCs .
Cat. No.: HY-164163
CAS No.: 2378428-24-9
Target:
Research Areas:
MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT (example 4-3) is an ADC drug-linker conjugate composed of an payload 7-MAD-MDCPT (HY-132162) and a linker MP-PEG8-Val-Lys-Gly (HY-179261), used for synthesizing ADC .
Cat. No.: HY-179204S
CAS No.: 2911575-77-2
Cat. No.: HY-183681S1
CAS No.: 3013694-23-7
Cat. No.: HY-171946
CAS No.: 2857037-73-9
Research Areas:
TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a drug-linker conjugate for ADC. TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT consists of a topoisomerase 1 inhibitor (Topi MF-6) (HY-175203) and a cleavable linker (Maleimide-Ph(3,5-F)-PEG4-Val-Ala) (HY-175218). TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT can be used for synthesis of ADCs .
Cat. No.: HY-184563S
CAS No.: 3086790-98-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
