Mal-Bal-Ph(β-D-Glucose)-7-MAD-MDCPT
Based on 1 Customer Validation
Mal-Bal-Ph(β-D-Glucose)-7-MAD-MDCPT (example 70) is an ADC drug-linker conjugate composed of the Camptothecin analog 7-MAD-MDCPT (HY-132162), and a Mal-Bal-Ph(β-D-Glucose) linker. DBCO-PEG2-C2-acid can be used to synthesize antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 99.06%
- CAS No.: 2396667-62-0
- Formula: C46H44N6O19
- Molecular Weight:984.87
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2396667-62-0
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Appearance Solid
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Molecular Weight 984.87
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Formula C46H44N6O19
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Color Light yellow to yellow
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SMILES
O=C(C=CC1=O)N1CCC(NCCC(NC(C=C2COC(NCC3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(OCO8)=C8C=C73)=O)=C(C=C2)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O)O)O)C(O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (101.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0154 mL | 5.0768 mL | 10.1536 mL | 25.3841 mL |
| 5 mM | 0.2031 mL | 1.0154 mL | 2.0307 mL | 5.0768 mL | |
| 10 mM | 0.1015 mL | 0.5077 mL | 1.0154 mL | 2.5384 mL | |
| 15 mM | 0.0677 mL | 0.3385 mL | 0.6769 mL | 1.6923 mL | |
| 20 mM | 0.0508 mL | 0.2538 mL | 0.5077 mL | 1.2692 mL | |
| 25 mM | 0.0406 mL | 0.2031 mL | 0.4061 mL | 1.0154 mL | |
| 30 mM | 0.0338 mL | 0.1692 mL | 0.3385 mL | 0.8461 mL | |
| 40 mM | 0.0254 mL | 0.1269 mL | 0.2538 mL | 0.6346 mL | |
| 50 mM | 0.0203 mL | 0.1015 mL | 0.2031 mL | 0.5077 mL | |
| 60 mM | 0.0169 mL | 0.0846 mL | 0.1692 mL | 0.4231 mL | |
| 80 mM | 0.0127 mL | 0.0635 mL | 0.1269 mL | 0.3173 mL | |
| 100 mM | 0.0102 mL | 0.0508 mL | 0.1015 mL | 0.2538 mL |