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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
AK2
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "AK2" in MCE Product Catalog:
5
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Itaconate-alkyne (ITalk) is a specific bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of Itaconation in living cells. Itaconate-alkyne, a functional analogue of Itaconate, exhibits comparable antiinflammatory effect with Itaconate and enables the labeling of bona fide targets of Itaconate . Itaconate-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-RS00506
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AK2 Human Pre-designed siRNA Set A contains three designed siRNAs for AK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18730
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Ak2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ak2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25217
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Ak2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ak2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-178936
CAS No.: 3094174-82-7
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JAK2-IN-15 is an orally active, potent, selective JAK2 inhibitor (IC50 = 1.17 nM). JAK2-IN-15 can inhibit the AK2-STAT signaling pathway. JAK2-IN-15 significantly improves key pathological indicators such as hematocrit and splenomegaly in an Epoetin beta (HY-114134) (rhEPO)-induced mouse model. JAK2-IN-15 can be used for the study of Polycythemia Vera (PV) .
Cat. No.: HY-161512
CAS No.: 229476-71-5
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hAChE/hBACE-1-IN-4 (compound AK-2) is a quinazoline derivative. hAChE/hBACE-1-IN-4 shows significant inhibitory activity against hAChE and hBACE-1 enzymes (hAChE, IC50=0.283 μM; hBACE-1, IC50=0.231 μM). hAChE/hBACE-1-IN-4 has the potential to inhibit Aβ aggregation. hAChE/hBACE-1-IN-4 has non-neurotoxicity , blood-brain barrier permeability and oral activity. hAChE/hBACE-1-IN-4 can be used in Alzheimer's disease research .
Cat. No.: HY-174999
CAS No.: 2914873-59-7
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JAK3-IN-18 is an orally active JAK3 and TEC inhibitor, with IC50s of 0.5391 nM and 12.40 nM, respectively. JAK3-IN-18 demonstrates outstanding selectivity over AK1, AK2, and TYk2, with selectivity ratios exceeding 10,000-fold. JAK3-IN-18 demonstrates excellent therapeutic efficacy in the experimental autoimmune encephalomyelitis (EAE) mouse model. JAK3-IN-18 can be used for the study of multiple sclerosis .
Cat. No.: HY-P702608
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AK2; ADK2; Adenylate Kinase 2; AK 2; Adenylate Kinase 2, Mitochondrial; Testis Secretory Sperm-Binding Protein Li 220n; Adenylate Monophosphate Kinase; Adenylate Kinase Isoenzyme 2, Mitochondrial; ATP-AMP Transphosphorylase 2; Adenylate Kinase 3; ATP:AMP
Cat. No.: HY-118674
CAS No.: 122508-12-7
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AK-2-38, a Nifedipine (HY-B0284) analogue, is a calcium channel antagonist. AK-2-38 also has partial agonist effects on isolated guinea pig left atrium .
Cat. No.: HY-174720
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Human EIF2AK2 mRNA encodes the human eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2) protein, a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. EIF2AK2 plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation.
Cat. No.: HY-RS04243
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EIF2AK2 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF2AK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18207
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Eif2ak2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif2ak2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24684
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Eif2ak2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif2ak2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P80283
Synonyms: PKR, PRKR, EIF2AK2, Eukaryotic translation initiation factor 2-alpha kinase 2, Interferon-inducible RNA-dependent protein kinase, P1/eIF-2A protein kinase, Protein kinase RNA-activated, Tyrosine-protein kinase EIF2AK2, p68 kinase, eIF-2A protein kinase 2, Protein kinase R
Cat. No.: HY-P704016
Purity: ≥ 70%, as determined by Bis-Tris PAGE.
Synonyms: EIF2AK2; Eukaryotic Translation Initiation Factor 2-Alpha Kinase 2; Prev. PRKR; Protein Phosphatase 1, Regulatory Subunit 83; PKR; Protein Kinase RNA-Regulated; Interferon-Induced, Double-Stranded RNA-Activated Protein Kinase; P1/EIF-2A Protein Kinase; Ty
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Cat. No.: HY-P86157
Synonyms: EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
Cat. No.: HY-P81299
Synonyms: EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
Cat. No.: HY-P81299A
Synonyms: EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
