2454181-83-8
Chemical Structure
Itaconate-alkyne
Synonym(s): ITalk
- CAS No.: 2454181-83-8
- Formula:C13H18O4
- Molecular Weight:238.28
IUPAC Name: 2-methylene-4-(oct-7-yn-1-yloxy)-4-oxobutanoic acid
InChIKey: NPWMZOZWVAFQMP-UHFFFAOYSA-N
SMILES: O=C(O)C(CC(OCCCCCCC#C)=O)=C
Biological Activity: Itaconate-alkyne (ITalk) is a specific bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of Itaconation in living cells. Itaconate-alkyne, a functional analogue of Itaconate, exhibits comparable antiinflammatory effect with Itaconate and enables the labeling of bona fide targets of Itaconate[1]. Itaconate-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Itaconate-alkyne | 98.01% | Itaconate-alkyne (ITalk) is a specific bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of Itaconation in living cells. Itaconate-alkyne, a functional analogue of Itaconate, exhibits comparable antiinflammatory effect with Itaconate and enables the labeling of bona fide targets of Itaconate. Itaconate-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Keywords
