1 Result for "

Ac-FLTD-CMK

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Ac-FLTD-CMK" in MCE Product Catalog:

12
12 Cited Publications
Cat. No.: HY-111675
CAS No.: 2376255-48-8
Purity:  99.53%
Target:  

Caspase Pyroptosis

Research Areas:  

Inflammation/Immunology

Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 μM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3 .
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