3 Results for "

Adefovir diphosphate

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Adefovir diphosphate" in MCE Product Catalog:

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Cat. No.: HY-168165
CAS No.: 129556-87-2
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Adefovir diphosphate is an antiviral compound with activity against hepatitis B virus (HBV). Adefovir diphosphate blocks the replication of HBV by inhibiting reverse transcriptase. Adefovir diphosphate has also shown activity against other viruses such as herpes viruses and human immunodeficiency virus. Adefovir diphosphate is used as an effective inhibitory option in the suppression of chronic hepatitis B. The mechanism of action of Adefovir diphosphate involves blocking the autophosphorylation of growth factor receptors, thereby potentially reducing the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B .
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2
2 Cited Publications
Cat. No.: HY-B1826
CAS No.: 106941-25-7
Synonyms: GS-0393; PMEA
Research Areas:  

Infection

Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses .
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Cat. No.: HY-B1826S2
CAS No.: 1190021-70-5
Synonyms: GS-0393-d4; PMEA-d4
Adefovir-d4 is the deuterium labeled Adefovir. Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses .
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