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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
Aldolase
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "Aldolase" in MCE Product Catalog:
9
Research Areas:
Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib can activate lysosomal adenosine monophosphate-activated protein kinase (AMPK) and decreases blood glucose. Aldometanib can be used for the research of metabolic homeostasis .
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1 Cited Publications
Synonyms: Triose phosphate
Research Areas:
Aldolase, Rabbit muscle (Fructose-diphosphate aldolase) is a glycolytic enzyme and glucose availability sensor. Aldolase, Rabbit muscle catalyzes the reversible carbon-carbon cleavage of fructose-1,6-bisphosphate to produce dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. Aldolase, Rabbit muscle is an essential component for v-ATPase activity. Aldolase, Rabbit muscle participates in processes such as gluconeogenesis, the Calvin cycle and glycolysis .
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Phosphoglycolohydroxamic acid is a potent aldolase and triose-phosphate isomerase inhibitor. Phosphoglycolohydroxamic acid can be used in the research of antibacterial and antifungal area .
Cat. No.: HY-W041994
CAS No.: 80307-12-6
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GMBS is a heterobifunctional crosslinker targeting primary amines and sulfhydryl groups. GMBS can be used for chemical crosslinking of proteins and crosslinking mass spectrometry (CXMS) to study protein folding and map interfaces between interacting proteins .
Target:
Cat. No.: HY-W012874
CAS No.: 632-20-2
Synonyms: H-D-Thr-OH
Research Areas:
FBA-IN-1 (compound 2a11) is a first-in-class, covalent and allosteric inhibitor of fructose-1,6-bisphosphate aldolase from Candida albicans (CaFBA). FBA-IN-1 inhibits the growth of Azole-resistant strains 103 with the MIC80 of 1 μg/mL .
Cat. No.: HY-E70075
Synonyms: GDH-TIM; GDH-TPI
Target:
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α-Glycerophosphate Dehydrogenase-Triosephosphate (GDH-TIM) is a bifunctional enzyme with activity toward glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. α-Glycerophosphate Dehydrogenase-Triosephosphate catalyzes the conversion of glyceraldehyde 3-phosphate to dihydroxyacetone phosphate. α-Glycerophosphate Dehydrogenase-Triosephosphate can utilize NADH to catalyze the reduction of dihydroxyacetone phosphate to glycerol-1-P .
Research Areas:
N-Acetylneuraminate lyase (CgNal) (Sialic acid aldolase (CgNal)) is a rate-limiting enzyme in bacteria metabolism that catalyzes the reversible aldol cleavage of sialic acid, and it regulates the overall metabolism of the bacterial sialic acid catabolic pathway. N-Acetylneuraminate lyase (CgNal) catalyzes the reversible condensation reaction of pyruvate and N-acetyl-d-mannosamine (ManNAc) to produce sialic acid N-acetylneuraminic acid (Neu5Ac). The protein expression of N-Acetylneuraminate lyase is downregulated at the translational level under the regulation of methyl methanesulfonate, and this change significantly impairs the adhesion and invasion abilities of bacteria to eukaryotic cells. N-Acetylneuraminate lyase is a key virulence-related protein in various pathogenic bacteria and is considered an antibiotic drug target. N-Acetylneuraminate lyase (CgNal) can be used in studies of invasive (extraintestinal) infectious diseases, Crohn's disease, and methicillin-resistant Staphylococcus aureus infections .
Cat. No.: HY-147064A
CAS No.: 1187-99-1
Cat. No.: HY-N13363
CAS No.: 27244-54-8
Cat. No.: HY-147064
Research Areas:
DL-4-Hydroxy-2-ketoglutarate lithium is one of the metabolites that is characteristically elevated in the urine of patients with type 3 primary hyperoxaluria (PH3), and it is produced by the accumulation of substrates of mitochondrial 4-hydroxy-2-oxoglutarate aldolase (HOGA). DL-4-Hydroxy-2-ketoglutarate lithium can be used in studies related to PH3 .
Cat. No.: HY-E70621
Research Areas:
Sialic acid aldolase (Pm NaNa) (EC 4.1.3.3) is a type I aldolase that catalyze the reversible aldol cleavage of N-acetylneuraminic acid (Neu5Ac) to form pyruvate and N-acetyl-D-mannosamine (ManNAc) with the equilibrium favoring the Neu5Ac cleavage .
Cat. No.: HY-W012874S
Synonyms: H-D-Thr-OH-d2
Cat. No.: HY-E71030
Research Areas:
Aldolase A, Human (EC 4.1.2.13) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A, Human (EC 4.1.2.13) , fused to His-tag at N-terminus, was expressed in E.coli.
Cat. No.: HY-E71513
Target:
Research Areas:
2-Dehydropantoate aldolase (EC 4.1.2.12) belongs to the lyase family and can cleave carbon-carbon bonds.
Cat. No.: HY-P2726A
Research Areas:
Aldolase, Spinach (EC 4.1.2.13) is an enzyme catalyzing a reversible reaction that splits the aldol, fructose 1,6-bisphosphate, into the triose phosphates dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P). Aldolase, Spinach (EC 4.1.2.13) can also produce DHAP from other (3S,4R)-ketose 1-phosphates such as fructose 1-phosphate and sedoheptulose 1,7-bisphosphate.
Cat. No.: HY-E71744
Target:
Research Areas:
3-Hydroxy-D-aspartate aldolase (EC 4.1.3.41) is a pyridoxal-phosphate protein.
Cat. No.: HY-E71071
Research Areas:
(4S)-4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.42) is specific for the (S) enantiomer.(4S)-4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.42) catalyses the reactions of EC 4.1.1.3, oxaloacetate decarboxylase and EC 4.1.2.14, 2-dehydro-3-deoxy-phosphogluconate aldolase.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
