3 Results for "

Alistipes

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Alistipes" in MCE Product Catalog:

Polymyxin B2
Polymyxin B2
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Cat. No.: HY-A0248B
CAS No.: 34503-87-2
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Inflammation/Immunology

Polymyxin B2 is a polypeptide antibiotic with particularly potent antibacterial activity against Gram-negative bacteria. Polymyxin B2 kills bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting membrane integrity and causing leakage of intracellular contents. Polymyxin B2 is used in studies related to Pseudomonas aeruginosa infection and acute enteritis .
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Canola oil
Canola oil
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Cat. No.: HY-N20666
CAS No.: 120962-03-0
Category:  

Brassica rapa var. oleifera de Candolle Lipids Plants Brassicaceae

Target:  

PPAR Fatty Acid Synthase (FASN) AMPK

Canola oil is an orally effective adipogenesis inhibitor and gut microbiota modulator. Canola oil inhibits the expression of PPARγ, SREBP1, SREBP2, Insig1 and Insig2, and increases the phosphorylation level of the AMPK pathway. Canola oil inhibits adipogenesis and reshapes gut microbiota in mice to ameliorate obesity . Canola oil can be used in obesity-related research .
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Castalagin
Castalagin
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Cat. No.: HY-N20707
CAS No.: 24312-00-3
Category:  

Acalypha australis L. Phenols Polyphenols Plants Fagaceae

Target:  

PARP Topoisomerase Penicillin-binding protein (PBP) PD-1/PD-L1 Bacterial Parasite

Castalagin is an orally active natural product with multiple biological activities including antibacterial activity against bacteria and anti-leishmanial activity against Leishmania aethiopica. Castalagin exhibits inhibitory activity against PARP1 and DNA topoisomerase II, with an IC50 of 0.86 μM for bovine PARP1. Castalagin reduces poly (ADP-ribosyl) ation modification in cells. Castalagin binds to the cell envelope of Ruminococcus bromii, increases the ratio of CD8+/FOXP3+CD4+ T cells in the tumor microenvironment, and acts as a prebiotic to enhance the activity of anti-PD-1 therapy. Castalagin induces morphological changes in Leishmania aethiopica promastigotes and inhibits their proliferation. Castalagin inhibits PBP2a-mediated peptidoglycan layer stabilization, disrupts bacterial peptidoglycan assembly, and inhibits and disintegrates bacterial biofilms. Castalagin can be used in research related to diseases such as cancer, leishmaniasis, and bacterial infections .
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