2 Results for "

BPN15606

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "BPN15606" in MCE Product Catalog:

Cat. No.: HY-117482
CAS No.: 1914989-49-3
Purity:  99.96%
Target:  

γ-secretase

Research Areas:  

Neurological Disease

BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN-15606 lowers Aβ42 and Aβ40 levels in the central nervous system of rats and mice. BPN-15606 has acceptable PK/PD properties, including bioavailability, half-life, and clearance .
loading...
    loading...
Cat. No.: HY-117482A
CAS No.: 2436239-00-6
Target:  

γ-secretase

Research Areas:  

Neurological Disease

BPN-15606 besylate is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN-15606 besylate lowers Aβ42 and Aβ40 levels in the central nervous system of rats and mice. BPN-15606 besylate has acceptable PK/PD properties, including bioavailability, half-life, and clearance .
loading...
    loading...