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Boc protecting groups

" in MedChemExpress (MCE) Product Catalog:

133

Inhibitors & Agonists

17

Biochemical Assay Reagents

38

Peptides

1

Isotope-Labeled Compounds

7

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W012001

    PROTAC Linkers Cancer
    Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    N-Boc-7-aminoheptanoic acid
  • HY-W010922

    Amino Acid Derivatives Others
    Fmoc-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bicyclic peptide tachykinin NK2 antagonists .
    Fmoc-Dap(Boc)-OH
  • HY-W007056

    Amino Acid Derivatives Biochemical Assay Reagents Drug Intermediate Infection
    Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa .
    Fmoc-N-me-Trp(Boc)-OH
  • HY-W047788

    Amino Acid Derivatives Others
    H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities .
    H-Dab(Boc)-OH
  • HY-42773

    1-Boc-1,8-diaminooctane

    PROTAC Linkers Cancer
    tert-Butyl (8-aminooctyl)carbamate (1-Boc-1,8-diaminooctane) can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    tert-Butyl (8-aminooctyl)carbamate
  • HY-W041856

    Boc-8-aminooctanoic acid

    PROTAC Linkers Cancer
    N-Boc-8-amino-octanoic acid (Boc-8-aminooctanoic acid) can be used as a PROTAC linker in the synthesis of PROTACs. N-Boc-8-amino-octanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    N-Boc-8-amino-octanoic acid
  • HY-W019032

    Amino Acid Derivatives Others
    Fmoc-D-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with antibacterial activity .
    Fmoc-D-Dab(Boc)-OH
  • HY-W047688

    1-Boc-1,10-diaminodecane

    PROTAC Linkers Cancer
    tert-Butyl (10-aminodecyl) carbamate (1-Boc-1,10-diaminodecane) is a synthetic intermediate that serves as a PROTAC linker in PROTAC synthesis and other conjugation applications. tert-Butyl (10-aminodecyl) carbamate is an alkane chain with a terminal amine and a Boc-protected amino group. The amine group can react with carboxylic acids, active NHS esters, carbonyl groups (ketones, aldehydes), etc. The Boc group can be deprotected under mild acidic conditions to form a free amine .
    tert-Butyl (10-aminodecyl)carbamate
  • HY-34738

    3-(Boc-amino)-1-propanol

    Amino Acid Derivatives Others
    Boc-β-Ala-ol (3-(Boc-amino)-1-propanol) is an alanine derivative with a Boc protecting group at the N-terminus, which can be used to synthesize bioactive peptide mimics, such as Nα-Benzoyl-α-azaornithine phenyl ester, which has trypsin inhibitory activity .
    Boc-β-Ala-ol
  • HY-W009229

    Biochemical Assay Reagents Others
    Boc-Glu(OtBu)-OH is a protected glutamic acid derivative with two protecting groups: Boc- and OTBu. Boc-Glu(OtBu)-OH can be used in the study of peptide compound synthesis .
    Boc-Glu(OtBu)-OH
  • HY-W077219

    Boc-Arg(Mtr)-OH

    Amino Acid Derivatives Others
    Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .
    Boc-L-Arg(Mtr)-OH
  • HY-W039729

    Biochemical Assay Reagents Others
    5-(Boc-amino)-1-pentanol is a linker containing a hydroxyl group and Boc-protected amino group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    5-(Boc-amino)-1-pentanol
  • HY-W101935

    N-Boc-D-arginine hydrochloride

    Amino Acid Derivatives Others
    N-Boc-D-Arg hydrochloride (N-Boc-D-arginine hydrochloride) is an amino acid derivative with a Boc protecting group, which can be used to synthesize desmopressin with the effects of improving nocturia, urinary incontinence and enuresis .
    N-Boc-D-Arg hydrochloride
  • HY-W575291

    N-Boc-oct-7-yn-1-amine

    Biochemical Assay Reagents Others
    tert-Butyl oct-7-yn-1-ylcarbamate (N-Boc-oct-7-yn-1-amine) is crosslinker consisting of a propargyl group and a t-Boc protected amine group. The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reactions. The t-Boc protected amine can be deprotected under mild acidic conditions.
    tert-Butyl oct-7-yn-1-ylcarbamate
  • HY-W1049061

    Biochemical Assay Reagents Others
    Boc-NH-PEG2000-COOH is a linear hetero-bifunctional PEG product with one Boc-protected amine and one carboxyl group. Boc-NH-PEG2000-COOH is an important cross-linker with PEG chains .
    Boc-NH-PEG2000-COOH
  • HY-W005828

    PROTAC Linkers Cancer
    9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. 9-(Boc-amino)nonanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    9-(Boc-amino)nonanoic acid
  • HY-140232B

    Biochemical Assay Reagents Others
    BOC-NH-PEG2000-NH2 is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG2000-NH2 is an important cross-linker with PEG chains .
    BOC-NH-PEG2000-NH2
  • HY-W259542

    Biochemical Assay Reagents Others
    O-Proparagyl-N-Boc-ethanolamine is crosslinker consisting of a propargyl group and a t-Boc protected amine group. The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reactions. The t-Boc protected amine can be deprotected under mild acidic conditions.
    O-Proparagyl-N-Boc-ethanolamine
  • HY-W005561

    Amino Acid Derivatives Others
    H-Dab(Boc)-OMe hydrochloride is an N-terminally protected diaminobutyric acid containing two protecting groups: methoxy (OMe) and tert-butyloxycarbonyl (Boc). H-Dab(Boc)-OMe hydrochloride can be used to synthesize the bifunctional chelator H3Dpaa that can rapidly complex 68Ga under physiological conditions .
    H-Dab(Boc)-OMe hydrochloride
  • HY-W101495

    N-Boc-L-leucine monohydrate

    Amino Acid Derivatives Others
    Boc-Leu-OH hydrate (N-Boc-L-leucine monohydrate) is an amino acid derivative with a Boc protecting group, which can be used to synthesize L-prolyl-L-leucyl-glycinamide peptide, a peptide mimetic with dopamine receptor modulatory activity .
    Boc-Leu-OH hydrate
  • HY-W008919

    N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester

    Amino Acid Derivatives Others
    Boc-Lys(Boc)-Onp (N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester) is a lysine with a Boc protecting group. Boc-Lys(Boc)-Onp was used as a substrate for a catalyst model to study its enzymatic hydrolysis reaction catalyzed by a copper(II) complex .
    Boc-Lys(Boc)-Onp
  • HY-42222

    Biochemical Assay Reagents Others
    N1,N5-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    N1,N5-Bis-boc-spermidine
  • HY-W089230

    N,N'-Di-tert-butoxycarbonyl-L-histidine

    Amino Acid Derivatives Others
    Boc-His(Boc)-OH (N,N'-Di-tert-butoxycarbonyl-L-histidine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize the dodecapeptide α-mating factor of Saccharomyces cerevisiae .
    Boc-His(Boc)-OH
  • HY-141253

    Biochemical Assay Reagents Others
    N-Boc-Tris is a protective reagent. N-Boc-Tris can utilize the Boc protecting group to protect amino groups in fields such as organic synthesis and pharmaceutical research and development, thereby avoiding unnecessary side reactions.
    N-Boc-Tris
  • HY-W009673

    N-Boc-L-pyroglutamic acid

    Amino Acid Derivatives Biochemical Assay Reagents Others
    Boc-Pyr-OH is a Boc-protected pyroglutamic acid derivative. Boc-Pyr-OH stabilizes the amino group of pyroglutamic acid through the Boc protecting group, preventing unwanted reactions during peptide synthesis. Boc-Pyr-OH can be used in the research of thyrotropin-releasing hormone (TRH) synthesis .
    Boc-Pyr-OH
  • HY-41063

    ADC Linker Cancer
    N-Boc-N-methyl-D-Valinol is an ADC linker with BOC protecting group.
    N-Boc-N-methyl-D-Valinol
  • HY-W010835

    Boc-S-trityl-D-cysteine

    Amino Acid Derivatives Others
    Boc-D-Cys(Trt)-OH (Boc-S-trityl-D-cysteine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize the bicyclic depsipeptide histone deacetylase inhibitor spirocysteine .
    Boc-D-Cys(Trt)-OH
  • HY-W089232

    PROTAC Linkers Cancer
    Boc-10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    Boc-10-Aminodecanoic acid
  • HY-W101723

    PROTAC Linkers Cancer
    Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    Boc-12-Ado-OH
  • HY-W089233

    N-Boc-D-glutaMic acid 1-tert-butyl ester

    Amino Acid Derivatives Others
    Boc-D-Glu-OtBu (N-Boc-D-glutaMic acid 1-tert-butyl ester) is an amino acid derivative with a Boc protecting group, which can be used to synthesize Adamant-1-yl tripeptide with immunostimulatory activity .
    Boc-D-Glu-OtBu
  • HY-78927

    Amino Acid Derivatives Others
    N-Boc-L-Prolinal is a proline with a Boc protecting group, which can be used to synthesize biologically active peptide mimetics, such as the synthesis of Dolastatin 10 (HY-15580) analogs with anti-colon cancer activity .
    N-Boc-L-Prolinal
  • HY-W014692

    N-t-Boc-amino-D-alanine; Boc-D-Dap-OH

    Amino Acid Derivatives Others
    Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize a potent NMDA receptor glycine site agonist with GluN2 subunit-specific activity .
    Boc-D-2,3-diaminopropionic acid
  • HY-140232D

    Biochemical Assay Reagents Others
    BOC-NH-PEG5000-NH2 is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG5000-NH2 is an important cross-linker with PEG chains .
    BOC-NH-PEG5000-NH2
  • HY-W101722

    PROTAC Linkers Cancer
    tert-Butyl (9-aminononyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    tert-Butyl (9-aminononyl)carbamate
  • HY-41062

    ADC Linker Cancer
    N-Boc-MeVal is an ADC linker with BOC protecting group .
    N-Boc-MeVal
  • HY-41064

    ADC Linker Cancer
    N-Boc-N-methyl-D-Valaldehyde is an ADC linker with a BOC protecting group.
    N-Boc-N-methyl-D-Valaldehyde
  • HY-W800658

    Biochemical Assay Reagents Others
    DBCO-PEG6-NH-Boc is a click chemistry reagent with a DBCO group and a Boc-protected amine. The DBCO can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of the compound.
    DBCO-PEG6-NH-Boc
  • HY-W101889

    N-Boc-N'-xanthyl-L-glutamine

    Amino Acid Derivatives Others
    Boc-Gln(Xan)-OH (N-Boc-N'-xanthyl-L-glutamine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antigenic activity .
    Boc-Gln(Xan)-OH
  • HY-W092176

    Biochemical Assay Reagents Others
    1,9-Bis-Boc-1,5,9-triazanonane is a linker containing two Boc-protected amino groups. The Boc groups can be deprotected under mild acidic conditions to form the free amines.
    1,9-Bis-boc-1,5,9-triazanonane
  • HY-W091365

    N-Boc-N'-xanthyl-L-asparagine

    Amino Acid Derivatives Others
    Boc-Asn(Xan)-OH (N-Boc-N'-xanthyl-L-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize locust fat growth hormone .
    Boc-Asn(Xan)-OH
  • HY-43781

    Biochemical Assay Reagents Others
    Fmoc-Lys(Boc)-PAB-OH is a peptide linker containing an Fmoc-protected amine and a Boc-protected lysine residue. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.
    Fmoc-Lys(Boc)-PAB-OH
  • HY-W591964

    Biochemical Assay Reagents Others
    t-Boc-Aminooxy-pentane-azide is a linker containing an azide group and Boc-protected amino group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    t-Boc-aminooxy-pentane-azide
  • HY-W109214

    Amino Acid Derivatives Others
    Fmoc-L-Dap(Boc,Me)-OH is a derivative of amino acid with protecting groups. Fmoc-L-Dap(Boc,Me)-OH can be used for synthesis of diaminopropionic acid containing peptide .
    Fmoc-L-Dap(Boc,Me)-OH
  • HY-42213

    Biochemical Assay Reagents Others
    N1,N4-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    N1,N4-Bis-Boc-spermidine
  • HY-W800828

    Biochemical Assay Reagents Others
    Iodoacetamido-PEG3-NHS ester is a PEG reagent containing an Iodoacetamide group and a Boc-protected amino group. The iodoacetamide group is an alkylating agent that can be used to bind covalently with the thiol group. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    Iodoacetamido-PEG3-NHS ester
  • HY-PS0015

    Biochemical Assay Reagents Others
    Fmoc-Lys(Boc)-Wang resin is a resin containing a lysine protecting group and can be used for the synthesis of peptides .
    Fmoc-Lys(Boc)-Wang resin
  • HY-W190958

    Biochemical Assay Reagents Others
    Boc-NH-Tri-(carbonylethoxymethyl)-methane is a branched PEG linker with a Boc-protected amino and three terminal carboxilic acid groups. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal carboxylic acid groups can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
    Boc-NH-Tri-(carbonylethoxymethyl)-methane
  • HY-W591977

    Biochemical Assay Reagents Others
    Boc-5-aminopentanoic NHS ester is a linker containing an NHS ester and a t-Boc protected amine group. The t-Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    Boc-5-aminopentanoic NHS ester
  • HY-W286613

    Biochemical Assay Reagents Others
    N-Boc-Biocytin is a biotin PEG linker containing a carboxylic group and Boc-protected amine. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The Boc group can be deprotected under acidic condition to obtain the free amine which can be used for further conjugations.
    N-Boc-Biocytin
  • HY-W088100

    N-Boc-N'-trityl-D-asparagine; Boc-D-Asn(Trt)-OH

    Amino Acid Derivatives Cancer
    Boc-N-gamma-trityl-D-asparagin (N-Boc-N'-trityl-D-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize metastasis-inhibiting or tumor growth-inhibiting metastasis-inhibiting MS derivatives .
    Boc-N-gamma-trityl-D-asparagin

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