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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
C1S
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "C1S" in MCE Product Catalog:
Cat. No.: HY-P991127
CAS No.: 2922766-89-8
Synonyms: DNTH103
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Cat. No.: HY-P99050
CAS No.: 2049079-64-1
Synonyms: BIVV009; IPN-009; TNT009
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Cat. No.: HY-P990091
CAS No.: 2756228-76-7
Synonyms: SAR 445088
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Cat. No.: HY-149278
CAS No.: 3033831-40-9
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Complement C1s-IN-1 is a potent, selective, orally active and cross the blood-brain barrier C1s inhibitor with an IC50 value of 36 nM [1].
Cat. No.: HY-50875
CAS No.: 217099-44-0
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BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
Cat. No.: HY-W371165
CAS No.: 1376162-36-5
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C1s-IN-1 trihydrochloride (Compound A1) is the selective inhibitor for C1s protease with the Ki of 5.8 μM. C1s-IN-1 trihydrochloride inhibits cleavage of C2 by C1s with an IC50 of 85 μM, inhibits the activation of classic pathway with an IC50 of 22 μM. C1s-IN-1 trihydrochloride is the competitive inhibitor for thrombin with the Ki of 51.2 μM [1].
Cat. No.: HY-P10827
CAS No.: 1356469-36-7
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Cat. No.: HY-P991629
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Cat. No.: HY-E70534
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C1s Proenzyme, the native form of C1s enzyme, is an inactive zymogen until C1 is activated. C1 complex binds to and is activated by antigen-antibody complexes (immune complexes) yielding C1r enzyme. C1r enzyme in the C1 complex activates C1s proenzyme generating C1s enzyme [1].
Cat. No.: HY-50874
CAS No.: 217099-43-9
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BCX 1470 inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
Cat. No.: HY-RS01737
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C1S Human Pre-designed siRNA Set A contains three designed siRNAs for C1S gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24256
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C1s Rat Pre-designed siRNA Set A contains three designed siRNAs for C1s gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E70390
Synonyms: masp-2, c1 esterase, c1-esterase
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C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity [1].
Cat. No.: HY-W371164
CAS No.: 1016866-61-7
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C1s-IN-1 (compound A1) is a selective and competitive inhibitor of C1s. C1s-IN-1 binds directly to C1s with a Kd of 9.8 μM [1].
Cat. No.: HY-P706123
Purity: ≥ 95%, as determined by reducing SDS-PAGE. ≥ 95%, as determined by HPLC.
Synonyms: Complement C1S; C1S; A0A2K5VQX9
Species:
Source:
Cat. No.: HY-P5528
Cat. No.: HY-P75463A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Complement C1S-A subcomponent; C1 esterase; C1Sa; C1S
Cat. No.: HY-158469
Purity: 98.91%
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
