Complement C1s Protein, Cynomolgus (HEK293, His)

C1s/Complement component C1s, a serine protease and B chain, forms C1 with C1q and C1r, initiating the classical complement pathway. Activated by C1r, C1s then activates downstream components C2 and C4, crucially driving the complement system cascade. Complement C1s Protein, Cynomolgus (HEK293, His) is expressed by HEK293 , with C-His labeled tag.

C1s, a serine protease, constitutes the B chain that, in conjunction with C1q and C1r, assembles to create C1, the initial component in the classical pathway of the complement system. Activation of C1s is facilitated by C1r, enabling it to subsequently activate downstream components C2 and C4, thereby initiating the cascade of events essential for complement system function.

Cynomolgus

HEK293

C-His

A0A2K5VQX9 (M1-D688)

102137207

Full Length of Mature Protein

EPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIMSGDTEEGRLCGQRTSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDAPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTVRREDFDVEPADSEGNCLDSLVFVAGDQQFGPYCGRGFPGPLNIETKSNALDIIFQTDLTGQNKGWKLRYHGDPMPCPKEETPTSVWEPAKAKYVFKDVVRITCLDGFEVVEGRVGATSFHSTCQSNGKWSNSKLKCQPVDCGIPESIENGKFEDPESTLFGSVTRYTCEEPYYYMENGGNGQYHCASNGSWVNEALSPELPKCVPVCGVPREPFEGKQRIIGGSDADIKNFPWQVFFDNPWAGGALIDEYWVLTAAHVVEGNQEPTMYVGSTSVQTSRLAKSKMLTSERVFIHPGWKLLEVPEARTNFDNDIALVQLKDPVKMGPTVAPICLPGTSSDYNLMDGDLGLIAGWGRTEKRDRALRLKAAMLPVAPLRKCREVKVENPKADAGAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYVAGLVSWGPQCGTYGLYTRVQNYVDWIKKTMQENSTPSKD

Approximately 92 kDa & 58 kDa & 31.8 kDa & 25.5 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

≥ 95%, as determined by reducing SDS-PAGE. ≥ 95%, as determined by HPLC.

<1 EU/μg, determined by LAL method.