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Results for "

CD163

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

3

Inhibitory Antibodies

1

Natural
Products

3

Recombinant Proteins

2

Antibodies

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Cat. No. Compare Product Name Species Source
  • HY-P700669
    CD163 Protein, Mouse (HEK293, His)

    M130; CD163 molecule; CD163; GHI/61; HbSR; MM130; RM3/1; SCARI1; sCD163

    		 Mouse HEK293
    CD163 protein is pivotal in macrophages for clearing and endocytosing hemoglobin/haptoglobin complexes, safeguarding tissues from oxidative damage. It contributes to iron recycling by facilitating complex endocytosis and heme breakdown, with calcium and pH influencing hemoglobin binding. This initiates intracellular signals involving tyrosine kinase, calcium mobilization, and cytokine secretion. The soluble form, sCD163, released through shedding, may have an anti-inflammatory role. CD163 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD163 protein, expressed by HEK293, with C-His labeled tag. The total length of CD163 Protein, Mouse (HEK293, His) is 1007 a.a., with molecular weight of 120-150 kDa.
  • HY-P77884
    CD163 Protein, Human (HEK293, His-Avi)

    M130; CD163 molecule; CD163; GHI/61; HbSR; MM130; RM3/1; SCARI1; sCD163

    		 Human HEK293
    CD163 Protein, an acute phase-regulated receptor, crucially clears hemoglobin/haptoglobin complexes via endocytosis in macrophages, protecting tissues from potential oxidative damage. Beyond iron uptake, CD163 exhibits calcium- and pH-dependent binding preferences, with higher affinity for hemoglobin/haptoglobin complexes of HP*1F phenotype. It triggers intracellular signals, including tyrosine kinase-dependent calcium mobilization, inositol triphosphate production, and IL6 and CSF1 secretion. CD163 shedding produces a soluble form (sCD163) with potential anti-inflammatory properties, a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions. CD163 Protein, Human (HEK293, His-Avi) is the recombinant human-derived CD163 protein, expressed by HEK293, with C-His, C-Avi labeled tag. The total length of CD163 Protein, Human (HEK293, His-Avi) is 1004 a.a., with molecular weight of 120-140 kDa.
  • HY-P700668
    CD163 Protein, Human (Biotinylated, HEK293, His-Avi)

    M130; CD163 molecule; CD163; GHI/61; HbSR; MM130; RM3/1; SCARI1; sCD163

    		 Human HEK293
    CD163 Protein, an acute phase-regulated receptor, crucially clears hemoglobin/haptoglobin complexes via endocytosis in macrophages, protecting tissues from potential oxidative damage. Beyond iron uptake, CD163 exhibits calcium- and pH-dependent binding preferences, with higher affinity for hemoglobin/haptoglobin complexes of HP*1F phenotype. It triggers intracellular signals, including tyrosine kinase-dependent calcium mobilization, inositol triphosphate production, and IL6 and CSF1 secretion. CD163 shedding produces a soluble form (sCD163) with potential anti-inflammatory properties, a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions. CD163 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD163 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of CD163 Protein, Human (Biotinylated, HEK293, His-Avi) is 1004 a.a., with molecular weight of 120-140 kDa.

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