2 Results for "

CD30+ malignancies

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CD30+ malignancies" in MCE Product Catalog:

Cat. No.: HY-P991638

Target:  

TNF Receptor

Research Areas:  

Cancer

XmAb-2513 is a humanized monoclonal antibody inhibitor targeting CD30. XmAb-2513 has significant anti-proliferative activity and superior antibody-dependent cell-mediated cytotoxicity (ADCC) as well as antibody-dependent cell-mediated phagocytosis (ADCP). XmAb-2513 can be used for hematologic malignancies like Hodgkin Lymphoma (HL) and Anaplastic Large Cell Lymphoma (ALCL) research .
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Cat. No.: HY-180412
CAS No.: 226072-63-5
Synonyms: BB-3644
Target:  

MMP

Research Areas:  

Cancer

Solimastat (BB-3644) is a potent metalloproteinase (MMP) inhibitor that blocks constitutive and antibody-stimulated CD30 shedding from cell surfaces with an IC50 of 180 nM. Solimastat enhances persistence of anti-CD30 antibody Ki-3 on cells and favors its internalization. Solimastat enhances cytotoxic activity of Ki-3.dgA towards CD30 + L540 cells. Solimastat can be used for the research of CD30 + malignancies .
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