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Results for "

CECR2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Epigenetic Reader Domain (8) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (8)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*NVS-CECR2-1*	Epigenetic Reader Domain Apoptosis	Cancer
NVS-CECR2-1, a non-BET family Bromodomain (BRD) inhibitor, is a potent and selective cat eye syndrome chromosome region, candidate 2 (CECR2) inhibitor. NVS-CECR2-1 binds to CECR2 BRD with high affinity (IC₅₀=47 nM; K_D=80 nM). NVS-CECR2-1 exhibits cytotoxic activity and induces apoptosis against various cancer cells by targeting CECR2 as well as via CECR2-independent mechanism .

CECR2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CECR2 Human Pre-designed siRNA Set A contains three designed siRNAs for CECR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CECR2 Human Pre-designed siRNA Set A CECR2 Human Pre-designed siRNA Set A

Cecr2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cecr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cecr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cecr2 Mouse Pre-designed siRNA Set A Cecr2 Mouse Pre-designed siRNA Set A

Cecr2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cecr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cecr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cecr2 Rat Pre-designed siRNA Set A Cecr2 Rat Pre-designed siRNA Set A

TP-238	Epigenetic Reader Domain	Cancer
TP-238 is a potent and selective dual *CECR2/BPTF* probe with IC₅₀ values of 30 nM and 350 nM, respectively. TP-238 also inhibits BRD9 with a pIC₅₀ of 5.9 and is less active against other 338 kinases ^[2].

TP-238 hydrochloride	Epigenetic Reader Domain	Cancer
TP-238 hydrochloride is a potent and selective dual *CECR2/BPTF* probe with IC₅₀ values of 30 nM and 350 nM, respectively. TP-238 hydrochloride also inhibits BRD9 with a pIC₅₀ of 5.9 and is less active against other 338 kinases ^[2].

GNE-886	Epigenetic Reader Domain	Cancer
GNE-886 (Compound 21) is a potent and selective inhibitor of Cat eye syndrome chromosome region candidate 2 bromodomain (CECR2) (BRD) with an IC₅₀ value of 0.016 µM and an EC₅₀ value of 370 nM. GNE-886 also inhibits BRD9 with an IC₅₀ value of 1.6 µM .

GSK232	Epigenetic Reader Domain	Cancer
GSK232 is a highly selective, cellularly penetrant *CECR2* inhibitor with excellent physicochemical properties.

GNE-375	Epigenetic Reader Domain	Cancer
GNE-375 is a potent and highly selective BRD9 inhibitor with an IC₅₀ of 5 nM. GNE-375 shows >100-fold selective for BRD9 over BRD4, TAF1, and CECR2. GNE-375 decreases BRD9 binding to chromatin .

Bromodomain IN-2	Epigenetic Reader Domain	Cancer
BD-IN-1 is a pan bromodomain (BD) inhibitor with K_D values of 250, 420, 130, 430, 67, 240, 970 nM for BRD4(1), CBP, BRPF1B, BRD7, BRD9, BRDT(1), CECR2 respectively. BD-IN-1 shows antiproliferative activity .

BAZ2-ICR 1 Publications Verification	Epigenetic Reader Domain	Cancer
BAZ2-ICR is a potent, selective, cell active and orally active BAZ2A/B bromodomains inhibitor with IC₅₀s of 130 nM and 180 nM, and K_ds of 109 nM and 170 nM, respectively. BAZ2-ICR shows 10-15-fold selectivity for binding *BAZ2A/B* over CECR2 and >100-fold selectivity over all other bromodomains. BAZ2-ICR is an epigenetic chemical probe .

Cat. No.	Compare	Product Name	Species	Source

	CECR1 Protein, Human (sf9, His) Adenosine deaminase 2; ADA2; ADGF; CECR1; IDGFL	Human	Sf9 insect cells
	CECR1, an adenosine deaminase, degrades extracellular adenosine, a pivotal signaling molecule, with activity dependent on elevated adenosine levels. It binds cell surfaces through proteoglycans, hinting at roles in cell proliferation and differentiation beyond its enzyme function. This dual functionality highlights its potential significance in cellular regulatory processes. CECR1 Protein, Human (sf9, His) is the recombinant human-derived CECR1 protein, expressed by Sf9 insect cells , with C-His labeled tag.

	CECR2 Protein, Human (His) CECR2; Cat eye syndrome critical region protein 2	Human	E. coli
	The CECR2 protein is a regulatory subunit in the CERF-1 and CERF-5 ISWI chromatin remodeling complexes that assembles ordered nucleosome arrays to help DNA enter replication, transcription, and repair. Despite lacking mononucleosome sliding ability, these complexes make crucial contributions to various developmental processes. CECR2 Protein, Human (His) is the recombinant human-derived CECR2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of CECR2 Protein, Human (His) is 114 a.a., .


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