1926989-06-1
1926989-06-1
Chemical Structure
GNE-375
- CAS No.: 1926989-06-1
- Formula:C25H29N3O5
- Molecular Weight:451.51
IUPAC Name: (E)-6-(but-2-en-1-yl)-4-(2,5-dimethoxy-4-(morpholine-4-carbonyl)phenyl)-2-methyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one
InChIKey: FWTDDBIMDSVPTR-AATRIKPKSA-N
SMILES: O=C1C(NC(C)=C2)=C2C(C3=CC(OC)=C(C(N4CCOCC4)=O)C=C3OC)=CN1C/C=C/C
Biological Activity: GNE-375 is a potent and highly selective BRD9 inhibitor with an IC50 of 5 nM. GNE-375 shows >100-fold selective for BRD9 over BRD4, TAF1, and CECR2. GNE-375 decreases BRD9 binding to chromatin[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GNE-375 | 99.93% | GNE-375 is a potent and highly selective BRD9 inhibitor with an IC50 of 5 nM. GNE-375 shows >100-fold selective for BRD9 over BRD4, TAF1, and CECR2. GNE-375 decreases BRD9 binding to chromatin. | ||||||||||||||||||||
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References
Keywords
